Control of conjugation in the plasmid pSf-R27
Citation:
Gareth Moss, 'Control of conjugation in the plasmid pSf-R27', [thesis], Trinity College (Dublin, Ireland). Department of Genetics, 2009, pp 286Download Item:
Abstract:
IncHI plasmids are prevalent amongst the Enterobacteriaceae and can confer a multi-drug resistance phenotype upon the host. IncHI plasmids are also thermosensitive for
conjugative transfer. Conjugation can occur optimally at 22°C to 30°C, but it is repressed at 37°C. pSf-R27 is a large and self-transmissible IncHI 1 plasmid. It encodes homologues to the transcriptional regulators H-NS, Dam, Hha and TlpA. These plasmid-encoded putative regulators are termed Sfh, DamR27, HhaR27 and TlpAR27 respectively. A role is shown for Sfh, HhaR27 and TlpAR27, but not DamR27 in modulating the conjugative transfer of pSf-R27 at 30°C.
Author: Moss, Gareth
Advisor:
Smith, CyrilQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). Department of GeneticsNote:
TARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ieType of material:
thesisAvailability:
Full text availableKeywords:
Genetics, Ph.D., Ph.D. Trinity College Dublin.Metadata
Show full item recordLicences: