TARA > Vice Deanery of Genetics & Microbiology >
Genetics (Scholarly Publications)
CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways.
Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2
Smac/Diablo antagonizes ubiquitin ligase activity of inhibitor of apoptosis proteins
Interchain proteolysis, in the absence of a dimerization stimulus, can initiate apoptosis-associated caspase-8 activation
Caspase-dependent inactivation of proteasome function during programmed cell death in Drosophila and man