RSS 1.0Genetics (Theses and Dissertations)
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Decoding the Genetics of Inherited Retinal Diseases in Ireland
(Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2019)Title: Decoding the Genetics of Inherited Retinal Diseases in Ireland Short Description: The Target 5000 study aims to provide genetic testing for the estimated 5,000 people in Ireland who are affected by a genetic retinal ... -
Transformation and marker gene removal strategies for the plastid genome of Brassica napus
(Trinity College (Dublin, Ireland). Department of Genetics, 2002)Despite the fact that the first transplastomic higher plant was produced more than a decade ago, transformation of the plastid genome and the regeneration of homoplasmic, fertile plants has so far been achieved in only 2 ... -
Cloning and functional characterisation of genes involved in cell death and cell survival
(Trinity College (Dublin, Ireland). Department of Genetics, 2004)During development and as a result of infection or injury, individual cells of multicellular organisms are required to mount appropriate survival or death responses. Two main signalling pathways are responsible for these ... -
Characterization of Arabidopsis homologs of the Drosophila SET domain gene Su(var)3-9
(Trinity College (Dublin, Ireland). Department of Genetics, 2004)SET domain-containing proteins encoded by the Drosophila gene Su(var)3-9 and its human homologue, SUV39H1, are major regulators of heterochromatin formation. The SET domains of these proteins carry histone methyltransferase ... -
On the role of caspase-recruitment domain proteins in apoptosis and NFkB activation
(Trinity College (Dublin, Ireland). Department of Genetics, 2002)Apoptosis and NFkB activation are two physiological processes that are essential for host mediated response to cellular injury. Apoptosis is a mechanism that removes damaged or unwanted cells. NFkB is a transcription factor ...
