RSS 1.0Genetics (Theses and Dissertations)
Browse by
Recent Submissions
-
The role of granzyme B and other granule proteases as modulators of cytokine activity
(Trinity College (Dublin, Ireland). Department of Genetics, 2012)Excerpt from introduction: In all vertebrate organisms a properly functioning immune system is absolutely required for protection against infectious agents and also acts as a safeguard against tumour development. Over time ... -
Genetic mechanisms establishing thalamocortical connectivity : novel genes and a role for Semaphorin6B
(Trinity College (Dublin, Ireland). Department of Genetics, 2015)One of the main functions of the brain is to process information from the environment. All input to the neocortex passes through the thalamus in order to be handled. Therefore, proper connectivity between the thalamus and ... -
A molecular genetic investigation of Irish origins
(Trinity College (Dublin, Ireland). Department of Genetics, 2000)Three hundred and ninety-four male DNA samples, from Ireland, Turkey and Togo, were genotyped for 5 X chromosome simple tandem repeat (STR) loci. Six Y chromosome STR loci and 8 Y chromosome unique event polymorphisms were ... -
Testing the hypothesis of genome duplications in vertebrates
(Trinity College (Dublin, Ireland). School of Genetics and Microbiology, 2000)The hypothesis that the human genome has undergone at least two rounds of genome duplication has become widely accepted, but has never been rigorously tested. In this study, several map-based inter- and intra-species ... -
Gene order evolution and genomic analyses of the model eukaryote, Saccharomyces cerevisiae, and other yeast species
(Trinity College (Dublin, Ireland). School of Genetics and Microbiology, 2000)The complete genome sequence of the yeast Saccharomyces cerevisiae can be used to form a clearer picture of the evolution of the diverse species of yeast and to construct a model of eukaryote genome evolution. In this study ...
