RSS 1.0School of Genetics & Microbiology
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Microbiology
Recent Submissions
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Blood-retina barrier regulation and sterile inflammation in retinal homeostasis and disease
(Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2019)Age-related macular degeneration (AMD) is the leading cause of central vision loss and blindness in the elderly. It is caused by a progressive loss of photoreceptors in the macula, thought to occur secondary to the damage ... -
Alternative routes to optimal expression levels: Evolutionary evidence for competitive RNAs and dosage compensation by gene duplication
(Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2019)Expression evolution and dosage constraints are important factors shaping genomic content and innovation. It has become increasingly clear that non-coding RNAs perform various regulatory functions in different cellular ... -
Contact transmission of influenza virus between ferrets imposes a looser bottleneck than respiratory droplet transmission allowing propagation of antiviral resistance
(2016)Influenza viruses cause annual seasonal epidemics and occasional pandemics. It is important to elucidate the stringency of bottlenecks during transmission to shed light on mechanisms that underlie the evolution and propagation ... -
Ferret airway epithelial cell cultures support efficient replication of influenza B virus but not mumps virus.
(2015)Ferrets have become the model animal of choice for influenza pathology and transmission experiments as they are permissive and susceptible to human influenza A viruses. However, inoculation of ferrets with mumps virus (MuV) ... -
Glycomic characterization of respiratory tract tissues of ferrets: Implications for its use in influenza virus infection studies
(2014)The initial recognition between influenza virus and the host cell is mediated by interactions between the viral surface protein hemagglutinin and sialic acid-terminated glycoconjugates on the host cell surface. The sialic ...
