Cell signalling and ADP ribosylation factor 1 (Arf1) effector proteins of African trypanosomes
Citation:
Miriam McAndrew, 'Cell signalling and ADP ribosylation factor 1 (Arf1) effector proteins of African trypanosomes', [thesis], Trinity College (Dublin, Ireland). Department of Genetics, 2008, pp 247Download Item:
Abstract:
The control of population size and differentiation status is essential for the survival of
all organisms. Tight regulation of these processes is of particular importance for
parasites. The African trypanosome, Trypanosoma brucei, represents a highly
successful parasite capable of surviving and indeed thriving in the harsh environment
in the bloodstream o f vertebrate hosts, and in the midgut and salivary glands of the
tsetse fly vector. This project seeks to address issues in relation to control mechanisms
of population size and differentiation status of mammalian-infective forms of the
African trypanosome via the identification, characterisation and elucidation of
components of the signalling process. This includes the identification of a putative
receptor/ transporter for a density controlling and differentiation signalling factor.
Author: McAndrew, Miriam
Advisor:
Murphy, NoelQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). Department of GeneticsNote:
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Full text availableKeywords:
Genetics, Ph.D., Ph.D. Trinity College DublinMetadata
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