Identification of Schistosoma mansoni adult male worm excretome-secretome and production of recombinant proteins with immunomodulatory potential
Citation:Julia Silveira Fahel, 'Identification of Schistosoma mansoni adult male worm excretome-secretome and production of recombinant proteins with immunomodulatory potential', [thesis], Trinity College (Dublin, Ireland). Department of Immunology, 2012, pp 306
Fahel TCD THESIS 9584 Identification of.pdf (PDF) 170.0Mb
Over two billion people worldwide are infected with helminth parasites. Helminths strongly modulate the host’s immune response in order to establish a balanced parasite- host dynamic. This helminth-derived immunomodulatory response does not only favour the parasite and host survival but also interferes with non related diseases that may occur to the host during the infection (I). Molecules released by the worm into the host’s blood circulation are the mostly likely to interact with immune cells therefoby mediating the immunomodulatory response. The aim of my Ph.D. is to identify and characterise immunomodulatory helminth-derived proteins.
Author: Fahel, Julia Silveira
Publisher:Trinity College (Dublin, Ireland). Department of Immunology
Type of material:thesis
Availability:Full text available