Browsing Clinical Medicine (Scholarly Publications) by Title
Now showing items 623-638 of 638
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Validation of a French version of the Breakthrough Pain Assessment Tool in cancer patients: factorial structure, reliability and responsiveness
(2023)Objective: Breakthrough cancer pain should be properly assessed for better-personalized treatment plan. The Breakthrough Pain Assessment Tool is a 14-item tool validated in English developed for this purpose; no French ... -
Validation of the EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis by disease content experts
(2017)The European League Against Rheumatism recommendations for the management of antineutrophil cytoplasmic antibody-associated vasculitis have been recently published. Unique to recommendation development, they were also voted ... -
Validation of two risk prediction models for recurrent falls in the first year after stroke: A prospective cohort study
(2017)Background: several multivariable models have been derived to predict post-stroke falls. These require validation before integration into clinical practice. The aim of this study was to externally validate two prediction ... -
Variants in linkage disequilibrium with the late cornified envelope gene cluster deletion are associated with susceptibility to psoriatic arthritis
(2010)Objective: A common deletion mapping to the psoriasis susceptibility locus 4 on chromosome 1q21, encompassing two genes of the late cornified envelope (LCE) gene cluster, has been associated with an increased risk of ... -
Vascular biomarkers of cognitive performance in a community-based elderly population: the Dublin Healthy Ageing study.
(2008)BACKGROUND: population studies suggest that cardiovascular risk factors may be associated with cognitive impairment. Epidemiological studies evaluating individual markers of vascular disease as risk factors for cognitive ... -
Vascular disease is associated with the expression of genes for intestinal cholesterol transport and metabolism
(2017)Context: Intestinal cholesterol metabolism is important in influencing postprandial lipoprotein concentrations, and might be important in the development of vascular disease. Objective: This study evaluated associations ... -
Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer
(2015)BACKGROUND: The VEGF pathway has become an important therapeutic target in lung cancer, where VEGF has long been established as a potent pro-angiogenic growth factor expressed by many types of tumors. While Bevacizumab ... -
Virtual brain biopsies in amyotrophic lateral sclerosis: diagnostic classification based on in vivo pathological patterns
(2017)Background: Diagnostic uncertainty in ALS has serious management implications and delays recruitment into clinical trials. Emerging evidence of presymptomatic disease-burden provides the rationale to develop diagnostic ... -
Virulent Mycobacterium tuberculosis Strains Evade Apoptosis of Infected Alveolar Macrophages
(2000)Human alveolar macrophages (AMφ) undergo apoptosis following infection with Mycobacterium tuberculosis in vitro. Apoptosis of cells infected with intracellular pathogens may benefit the host by eliminating a supportive ... -
Vital signs in palliative care: a scoping review
(2023)Vital signs are routinely measured in secondary healthcare settings and can be used to detect clinical problems, guide treatment, and monitor response to treatment. Vital signs are less frequently measured in palliative ... -
Von Willebrand factor propeptide in severe coronavirus disease 2019 (COVID-19): evidence of acute and sustained endothelial cell activation
(2021)Endothelial cell (EC) activation plays a key role in the pathogenesis of pulmonarymicrovascular occlusion, which is a hallmark of severe coronavirus disease 2019(COVID-19). Consistent with EC activation, increased plasma ... -
What does the ALSFRS-R really measure? A longitudinal and survival analysis of functional dimension subscores in amyotrophic lateral sclerosis
(2017)Introduction: ALSFRS-R is the most widely used functional rating system in ALS patients. However, heterogeneity in ALSFRS-R progression renders analysis challenging. We have explored the characteristics of total ALSFRS-R, ... -
Women's compliance with current folic acid recommendations and achievement of optimal vitamin status for preventing neural tube defects.
(2011)BACKGROUND The timing of folic acid supplement usage is critical to preventing pregnancies affected by neural tube defects (NTDs) because the neural tube closes by Day 28 post-conception. We investigated compliance of ... -
Xerostomia in patients with advanced cancer: a scoping review of clinical features and complications
(2023)Background: The aim of this project was to review the literature on dry mouth / xerostomia in patients with advanced cancer, with the objectives being to determine its prevalence, clinical features, and complications. Methods: ...
