RSS 1.0Clinical Medicine
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Clinical Medicine (Scholarly Publications)
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Clinical Medicine (Theses and Dissertations)
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The protective association of endogenous immunoglobulins against sepsis mortality is restricted to patients with moderate organ failure
(Springer Paris, 2017)Background Pre-evaluation of endogenous immunoglobulin levels is a potential strategy to improve the results of intravenous immunoglobulins in sepsis, but more work has to be done to identify those patients who could ... -
An investigation of epigenetic effects in Atherosclerosis
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2017)Epigenetic mechanisms may explain some of the missing heritability associated with CVD and how external factors such as diet, environment and lifestyle contribute to disease development and progression. This thesis aimed ... -
Effects of bile acids and fatty acids on cell signalling in human colorectal cancer cells
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2005)Colorectal cancer is a multifactorial disease. The interplay between genetic and environmental factors leads to the development of CRC. There have been great advancements in the knowledge of genetic alterations leading to ... -
Novel mediators regulating innate and adaptive type 17 immune responses
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2014)The discovery of a third subset of T helper cells and more recently innate T cell subsets which preferentially express IL-17A has led to intensive investigation into the roles these cells play in both host defence and ...
