Clinical Medicine
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Clinical Medicine (Scholarly Publications)
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Clinical Medicine (Theses and Dissertations)
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Leveraging a national patient registry to explore relapse in ANCA associated vasculitis
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2023)BACKGROUND ANCA associated vasculitis (AAV) is an archetypal rare autoimmune disease, resulting in immune-mediated organ damage. It has a relapsing-remitting course, resulting in cumulative morbidity and mortality. Toxic ... -
The Neuroimaging Features of Frontotemporal Dementia: Characterising Phenotype-Associated Pathological Changes In Vivo
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2023)Frontotemporal dementia (FTD) is a rare type of dementia. It can affect language, behaviour and memory depending on what part of the brain is involved. It can be difficult to diagnose, especially in the early stages of ... -
Real-world outcomes with recombinant factor IX Fc fusion protein in people with haemophilia B in Ireland
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2023)Haemophilia B is a rare X-linked bleeding disorder resulting from a deficiency of clotting factor IX (FIX), with severe haemophilia B defined as FIX levels < 0.01 IU/mL. Severe haemophilia is characterised by haemarthrosis, ... -
A Longitudinal Study of the Evolution of Neuropsychological Change in Amyotrophic Lateral Sclerosis: The Incidence, Nature and Progression of Language Impairment.
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2020)Background: Amyotrophic Lateral Sclerosis is a multi-system disease that also affects cognition and behaviour. Cognitive change in ALS manifests most commonly as executive dysfunction. Although changes in language function ... -
COVID-19 in Irish Hospital Healthcare Workers; SARS-CoV-2 antibody prevalence, epidemiology of infection and antibody response to vaccination
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2023)Background Hospital healthcare workers (HCW) are at increased risk of contracting COVID-19 infection. We aimed to determine the seroprevalence of SARS-CoV-2 antibodies in HCW in Ireland in two locations with diverging ...