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  A Follow up Study Evaluating the Effects of HIV Related Cognitive Impairment 

  Zaporojan, Lilia (Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2020)

  Study background: The introduction and availability of highly active antiretroviral therapy (HAART) led to an increased life expectancy among people living with HIV (PLWH) and reduced the incidence of HIV associated dementia ...
• IL-1 family members in health and disease 

  Doyle, Sarah L.; Brint, Elizabeth; Kamradt, Thomas (2019)

  In 1985, two distinct cDNAs encoding proteins sharing human Interleukin-1 (IL-1) activity were described, thus defining the first two members of the IL-1 family – IL-1α and IL-1β. These potent pro-inflammatory cytokines ...
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  Investigation into the Pathophysiology and the Objective Neurophysiological Measurement of Cancer-Related Fatigue in a Pre-Treatment Cancer Cohort 

  O'HIGGINS, CIARA MARIE (Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2020)

  Cancer-related fatigue (CRF) is one of the most common, debilitating, highly prevalent and unrelenting symptom experienced by patients through all stages of the cancer trajectory and often into survivorship (Berger et al., ...
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  Molecular Evaluation of Enzalutamide Resistance in Prostate Cancer 

  AIRD, JOHN (Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2020)

  Prostate cancer is a leading cause of cancer related death in men. As prostate cancer cells are dependent on androgen receptor (AR) signalling for continued growth, anti-androgen therapy is initially effective in treating ...
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  Lower gastrointestinal symptoms and symptoms-based triaging systems are poor predictors of clinical significant disease on colonoscopy 

  Mc Namara, Deirdre; Ismail, Mohd Syafiq; Aoko, Olufemi; Sihag, Sandeep; Connolly, Eimear; Omorogbe, Joseph; Semenov, Serhiy; O'Morain, Neil; O'Connor, Anthony; Breslin, Niall; Ryan, Barbara (2020)

  Introduction: Lower gastrointestinal symptoms (LGS) are a common cause of referral to the gastroenterology service. International guidelines are available to prioritise referrals. Some studies have reported that symptoms ...

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