Clinical Medicine
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Clinical Medicine (Scholarly Publications)
Clinical Medicine (Scholarly Publications) -
Clinical Medicine (Theses and Dissertations)
Clinical Medicine (Theses and Dissertations)
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Investigating a role for SARM1 in retinal degeneration
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2024)Retinal degenerative diseases, such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD), represent a leading cause of incurable blindness worldwide. RP is a genetically inherited retinal degeneration ... -
Profiling Serum and Tissue Biomarkers of Vedolizumab Therapy Response in Inflammatory Bowel Disease.
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2024)Introduction: Vedolizumab (VDZ) is a novel biologic agent proven effective for Inflammatory bowel disease (IBD), however, a significant proportion of patients do not respond to VZD treatment Aims: This thesis evaluates ... -
Exploring the effects of time-restricted eating as a novel intervention in patients with polycystic ovarian syndrome
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2024)Introduction: Polycystic ovarian syndrome (PCOS) is associated with hyperinsulinemia, insulin resistance and a high lifetime risk of developing type-2 diabetes mellitus. While many dietary interventions have been tested ... -
The Role of EUS and Proteomic Analysis in the Management and Surveillance of Pancreatic Cystic Lesions
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2024)Introduction Pancreatic cystic lesions (PCL) can be precursors to pancreatic cancer. The incidence of PCL are increasing worldwide with increased patient age and reliance on cross sectional imaging. However, not all PCL ... -
Network Analysis in Amyotrophic Lateral Sclerosis during Voluntary Motor Task: Neurophysiological Biomarkers of Disrupted Cortical Connections
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2024)Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disease that causes degeneration of both upper and lower motor neurons primarily affecting the motor system, but individual people with ALS show ...