RSS 1.0Clinical Medicine
Browse by
Collections in this Academic/Research Unit
-
Clinical Medicine (Scholarly Publications)
Clinical Medicine (Scholarly Publications) -
Clinical Medicine (Theses and Dissertations)
Clinical Medicine (Theses and Dissertations)
Recent Submissions
-
Motor and extra-motor involvement in amyotrophic lateral sclerosis
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2019)Amyotrophic Lateral Sclerosis (ALS) is primarily associated with pathology in the motor cortex and corticospinal tract. Based on clinical observations, it is increasingly recognised that extra-motor symptoms add to the ... -
Vitamin D deficiency: cognition, mortality and resource utilisation - prospective associations
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2019)Introduction: The association between Vitamin D and bone health has long been known. In recent times there has been increasing research into the effects of Vitamin D beyond this well-established link. Although there has ... -
Candidate role for TLR3 L412F in disease progression in Idiopathic Pulmonary Fibrosis (IPF) during bacterial and viral infection
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2019)In this thesis, we investigated the mechanisms by which TLR3 Leu412Phe (L412F) promotes disease progression in idiopathic pulmonary fibrosis (IPF) patients. IPF is a fatal interstitial lung disease of unknown aetiology and ... -
Synthesis and characterisation of aerosolised MIF inhitibitors for the treatment of respiratory disease
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2019)The main focus of this PhD thesis was to investigate the synthesis and characterisation of an aerosolised poly lactic-co-glycolic acid (PLGA) nanodrug delivery system for MIF enzyme inhibitors to modulate the physiological ... -
Polyunsaturated fatty acids, macrophages, and mediators of atherosclerosis: an in vitro investigation
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2004)Many cells are involved in the atherosclerotic process, but macrophages are present inevery phase of atherosclerosis and are heavily implicated as prime culprits in the molecular events that initiate, promote and complicate ...
