| dc.contributor.advisor | Atkins, Gregory | |
| dc.contributor.author | İskender, Güniz | |
| dc.date.accessioned | 2017-01-19T12:25:02Z | |
| dc.date.available | 2017-01-19T12:25:02Z | |
| dc.date.issued | 2010 | |
| dc.identifier.citation | Güniz İskender, 'Construction and development of simliki forest virus vectors for transient gene therapy of model tumours in mice', [thesis], Trinity College (Dublin, Ireland). Department of Microbiology, 2010, pp 250 | |
| dc.identifier.other | THESIS 9432 | |
| dc.identifier.uri | http://hdl.handle.net/2262/79056 | |
| dc.description.abstract | Cancer is a molecular and genetic disease that results from multiple alterations of genes, including proto-oncogenes and tumour-suppressor genes. Virotherapy is a branch of cancer gene therapy where oncolytic viruses are used to treat cancerous cells. Semliki Forest virus (SFV) and its derived vectors (recombinant or replication- competent) have been utilised for the treatment of cancer by exploiting their inherent apoptosis-inducing ability or by expressing high amounts of therapeutic proteins. | |
| dc.format | 1 volume | |
| dc.language.iso | en | |
| dc.publisher | Trinity College (Dublin, Ireland). Department of Microbiology | |
| dc.relation.isversionof | http://stella.catalogue.tcd.ie/iii/encore/record/C__Rb14881928 | |
| dc.subject | Microbiology, Ph.D. | |
| dc.subject | Ph.D. Trinity College Dublin | |
| dc.title | Construction and development of simliki forest virus vectors for transient gene therapy of model tumours in mice | |
| dc.type | thesis | |
| dc.type.supercollection | thesis_dissertations | |
| dc.type.supercollection | refereed_publications | |
| dc.type.qualificationlevel | Doctoral | |
| dc.type.qualificationname | Doctor of Philosophy (Ph.D.) | |
| dc.rights.ecaccessrights | openAccess | |
| dc.format.extentpagination | pp 250 | |
| dc.description.note | TARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie | |
