RSS 1.0Microbiology (Theses and Dissertations)
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Accelerated Evolution of Lager Yeast Strains for Improved Flavour Profiles
(Trinity College Dublin. School of Genetics & Microbiology. Discipline of Microbiology, 2022)S. pastorianus is an interspecific hybrid resulting from natural hybridization between S. cerevisiae and S. eubayanus. These two species belong to the Saccharomyces genus, a genus that encompasses different species related ... -
Drug Repurposing as a Strategy to Uncover Effective Antibacterial Compounds using Salmonella as a model
(Trinity College Dublin. School of Genetics & Microbiology. Discipline of Microbiology, 2021)Without doubt, antimicrobial resistance (AMR) is one of the most serious global challenge for public, animals and environmental health. Tackling this huge issue that is threatening modern medicine, is an urgent priority ... -
Investigating the interplay between the Tup1-Cyc8 and Swi-Snf chromatin remodelling complexes in Saccharomyces cerevisiae
(Trinity College Dublin. School of Genetics & Microbiology. Discipline of Microbiology, 2021)Swi-Snf is an ATP dependent chromatin remodelling complex which acts as a co-activator of gene transcription by its ability to open up densely packed chromatin by removal of nucleosomes. Conversely, Tup1-Cyc8 ... -
Impact of Metabolites on the Intestinal Mucosa and Development of Inflammation
(Trinity College Dublin. School of Genetics & Microbiology. Discipline of Microbiology, 2021)The intestinal epithelial mucosal barrier plays a pivotal role in the maintenance of intestinal homeostasis, acting as an important barrier between microbes and the host s innate immune system. The metabolite-rich environment ... -
Functional characterisation of small RNAs in Acinetobacter baumannii using Hi-GRIL-seq
(Trinity College Dublin. School of Genetics & Microbiology. Discipline of Microbiology, 2021)Acinetobacter baumannii is a priority pathogen that is a leading source of nosocomial multidrug resistant (MDR) infections worldwide. A key to the success of A. baumannii is the ability to quickly adapt to changing ...
