Histological changes associated with wheat protein antibodies in the absence of villous atrophy.
Citation:
O'Farrelly, C, Graeme-Cook, F, Hourihane, DO, Feighery, C, Weir, DG, Histological changes associated with wheat protein antibodies in the absence of villous atrophy., Journal of Clinical Pathology, 40, 10, 1987, 1228-30Download Item:
J Clin Pathol-1987-O'Farrelly-1228-30.pdf (PDF) 438.1Kb
Abstract:
A retrospective study was conducted to assess the association of alpha-gliadin antibodies with intraepithelial lymphocyte counts. Twelve subjects with apparently normal small intestinal histology and raised alpha-gliadin antibody titres had significantly increased intraepithelial lymphocyte counts (42 (SEM) 5.9) when compared with 16 subjects with normal alpha-gliadin antibody titres (17 (3.2); p less than 0.001). These findings show that in the absence of gross pathology raised alpha-gliadin antibody titres are associated with increased numbers of intraepithelial lymphocytes and may reflect continuous immunological processes in the small intestine
Author's Homepage:
http://people.tcd.ie/ofarreclDescription:
PUBLISHED
Author: O'FARRELLY, CLIONA
Type of material:
Journal ArticleCollections:
Series/Report no:
Journal of Clinical Pathology40
10
Availability:
Full text availableKeywords:
alpha-gliadin antibodiesSubject (TCD):
Immunology, Inflammation & InfectionLicences: