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Functional Relevance of Interleukin 8 Haplotype for the Innate Immune System in Holstein-Friesian Cattle
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2021)Calves rely heavily on their innate immune response in the post-birth period before their adaptive immune system develops. Interleukin 8 (IL-8) is a major chemoattractant predominantly associated with neutrophils response ... -
The activation of unconventional T cells by Staphylococcus aureus
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2021)Staphylococcus aureus is a major human pathogen of multiple tissue sites. The emergence of antibiotic-resistant strains promises greater morbidity in the future. No S. aureus vaccine has so far succeeded in translating ... -
IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F + neutrophils
(2021)Understanding the mechanism of protective immunity in the nasal mucosae is central to the design of more effective vaccines that prevent nasal infection and transmission of Bordetella pertussis. We found significant ... -
The Effects of Trained Innate Immunity on T Cell Responses; Clinical Implications and Knowledge Gaps for Future Research
(2021)The burgeoning field of innate immune training, also called trained immunity, has given immunologists new insights into the role of innate responses in protection against infection and in modulating inflammation. Moreover, ... -
Correction: IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F+ neutrophils
(2021)The original version of this article unfortunately contained a mistake in Fig. 3h. Due to a typesetting error the lines on the graph have been moved below the X axis. We apologize for this error. The correct Fig. 3h can ...
