Collections in this Academic/Research Unit

Recent Submissions

  • An integrated approach to oral vaccination against enteric pathogens 

    Davitt, Christopher (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2014)
    While the majority of human pathogens infect the body through mucosal sites, most licenced vaccines are injectable. In fact the only mucosal vaccine that is widely used for infant and childhood vaccination programs is the ...
  • In vivo and ex vivo examination of the safety of oats in coeliac disease 

    Cooper, Sarah (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2015)
    Coeliac disease is a chronic autoimmune disorder of the small intestine characterised by infiltration of intraepithelial lymphocytes, crypt hyperplasia and villous atrophy. It develops in genetically susceptible individuals ...
  • An investigaton of the innate immune response to the vaccine adjuvant chitosan 

    Carroll, Elizabeth (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2015)
    Vaccination is widely regarded as one of the most successful medical intervention strategies to have been introduced. Despite its resounding success, significant challenges in the field of vaccine research still remain. ...
  • Analysis of mitochondrial proteomes and supercomplex structures in brain tissue 

    Brady, Laura (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2015)
    Mitochondria play a complex multifactorial role in the control of cell bioenergetics. A primary function of mitochondria is the production of adenosine 5'-triphosphate (ATP) by the process of oxidative phosphorylation that ...
  • The role of Mal in alveolar macrophage-mediated resistance to Bordetella pertussis 

    Bernard, Nicholas J. (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2014)
    There is a global resurgence in pulmonary infection with Bordetella pertussis, the causative agent of whooping cough. B. pertussis is known to encode a number of virulence factors, some of which can function as pathogen-associated ...

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