RSS 1.0Biochemistry
Browse by
Collections in this Academic/Research Unit
-
Biochemistry (Scholarly Publications)
Biochemistry (Scholarly Publications) -
Biochemistry (Theses and Dissertations)
Biochemistry (Theses and Dissertations)
Recent Submissions
-
Development of Novel Anti-Trypanosomal Compounds via Computational, In Vitro and In Vivo Methods
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2018)Human African Trypanosomiasis is a neglected parasitic disease caused by Trypanosoma brucei, which if left untreated eventually leads to coma and death. With no successful vaccine to date, treatment relies on chemotherapy. ... -
IL-33 regulates the immune response to particulate vaccine adjuvants
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2018)Vaccines are one of the most successful tools contributing to global health. Despite their success, further research into safe and efficient vaccination is required to address two key issues; to combat emerging infectious ... -
Investigating the role of cell wall-anchored proteins during Staphylococcus aureus skin infection and as vaccine antigens
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2018)Staphylococcus aureus has become increasingly resistant to antibiotics and community acquired methicillin resistant S. aureus (CA-MRSA) skin and soft tissue infections (SSTIs) are occurring with increasing frequency in ... -
Malonylation of GAPDH in the inflammatory response in macrophages
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2018)Succinylation and malonylation are two recently discovered protein post-translational modifications. They involve the attachment to lysines of metabolism-derived succinyl and malonyl groups respectively, resulting in a ... -
In-depth Analytical Platforms Facilitating Serum Glycome, Proteome and Glycoproteome Investigation for Biomarker Discovery
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2018)Human serum is a great source of potential protein disease biomarkers because of how blood interacts with all parts of the body, allowing it to contain proteins secreted from specific tissues of interest, and due the ...
