RSS 1.0Biochemistry
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Biochemistry (Theses and Dissertations)
Recent Submissions
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Synthesis of chemical probes targeting membrane proteins
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2019)Membrane proteins carry out important physiological functions, including roles as enzymes and receptors, and are the targets for 50% of current drugs on the market,1 indicating their pharmacological importance. Knowledge ... -
Inflammation and uterine disease in the postpartum dairy cow
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2019)Following calving, inflammation of the uterus is common during the first week postpartum and is essential for the reparative process of involution. However, whilst the majority of cows resolve this inflammation a significant ... -
Adjuvants targeting innate T lymphocytes for improved oral vaccination
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2019)Effective mucosal vaccines can provide protective local and systemic immunity. Oral vaccination in particular has the potential to offer a safer and more efficacious approach than injection-based approaches, especially ... -
Inhibitor of Apoptosis Proteins as Targets for the Treatment of Malignant Rhabdoid Tumours
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2019)Malignant rhabdoid tumor (MRT) is a rare paediatric cancer which unfortunately is highly refractive to treatment. Retrospective reviews commonly place the survival rate at approximately 30-35 %. Thus, there is an urgent ...
