RSS 1.0Biochemistry
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Biochemistry (Scholarly Publications)
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Biochemistry (Theses and Dissertations)
Recent Submissions
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Immunomodulatory therapies for autoimmune diseases
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2019)Multiple sclerosis (MS) and psoriasis are both T cell mediated autoimmune diseases that are triggered in genetically susceptible individuals in response to environmental factors. Th17 cells are strongly implicated in the ... -
Factors influencing the induction of immune responses with DNA vaccines
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2002)Compared with any other medical discovery vaccines have prevented more deaths and suffering. Emergence of novel pathogens accentuates the requisite for ongoing development and improvement of traditional vaccination strategies. ... -
An investigation into the expression and physiological function of mitochondrial uncoupling proteins
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2004)Our study provides evidence that rat thymus contains a functioning mitochondrial uncoupling protein (UCP 1). Using reverse transcriptase-polymerase chain reaction (RT-PCR), we showed that rat thymus contains UCP 1 mRNA. ... -
Analysis of the MAPK pathways, in silico and in vitro
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2002)This thesis takes a combined computational and experimental approach to study the MAPK pathways. These proteins were chosen as they are highly conserved in both sequence and function across all eukaryotes. An evolutionary ... -
Local cellular and humoral immunity to Bordetella pertussis
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2004)The development of whole cell vaccine (Pw) and acellular pertussis vaccines (Pa) has had a huge impact on the incidence of whooping cough worldwide. The traditional Pw had high protective efficacy, but were associated with ...
