RSS 1.0Biochemistry
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Biochemistry (Theses and Dissertations)
Recent Submissions
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A role for microRNA-21 in the regulation of gastrointestinal health and disease
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2017)The gastrointestinal (GI) tract is a crucial site of innate and adaptive immune regulation, balancing tolerance of beneficial commensal microorganisms and reaction to invading pathgens. Pattern recognition receptors (PRRs), ... -
The role of T cell subsets in experimental autoimmune encephalomyelitis
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2015)Multiple Sclerosis (MS) is a chronic, demyelinating disease which affects the central nervous system (CNS) resulting in progressive cognitive decline and physical disability. Experimental autoimmune encephalomyelitis (EAE) ... -
Sterol regulatory element binding protein is a crucial regulator of natural killer cell metabolism and function
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2016)Natural Killer (NK) cells are a lymphocyte subset that has a key role in anti-viral and anti-tumour immunity. While the concept of immunometabolism has recently been recognised as critical in determining functions of immune ... -
Vaccine-induced protective immunity to Bordetella pertussis
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2016)Whooping cough (pertussis) is an infectious disease caused by the respiratory pathogen Bordetella pertussis that is re-emerging in many developed countries, despite extensive vaccine coverage. One of the proposed reasons ... -
Modulation of innate and adaptive immunity by Fasciola hepatica
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2018)Helminth parasites have developed highly effective mechanisms of immune subversion that helps prolong their survival in the host, resulting in the development of chronic infections. A bystander effect ...
