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Recent Submissions

  • α-Lactalbumin-oleic acid complex : structure function dynamics 

    Xie, Yongjing (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2015)
    Human alpha-lactalbumin made lethal to tumor cells (HAMLET) and its analogues are partially unfolded protein-oleic acid complexes that exhibit selective tumoricidal activity normally absent in the native protein itself, ...
  • Regulation of the immunomodulatory cytokine IL-10 by Twist2 

    Van den Bosch, Mirjam W. M. (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2014)
    Dysregulation of cytokines can lead to infectious and inflammatory diseases. The anti-inflammatory cytokine IL-10 is known to control pro-inflammatory cytokines such as TNF-a, IL-6 and IL-12. The regulation of IL-10 is ...
  • The role of Ets2 in the regulation of microRNA-155 

    Quinn, Susan (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2014)
    MicroRNA-155 (miR-155) is highly expressed in many cancers such as B cell lymphomas and myeloid leukaemia, and inflammatory disorders such as rheumatoid arthritis, atopic dermatitis and multiple sclerosis. The role of ...
  • In Vitro screening of novel compounds to assess their potential as anti-cancer, biological imaging and anti-inflammatory agents 

    Orange, Kim N. (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2015)
    Gold nanoparticles (AuNps) are some of the most extensively studied nanomaterials. Because of their biocompatibility, unique size- and shape- dependence, optoelectronic and catalytic properties, AuNps have attracted enormous ...
  • Activation and function of mucosal gamma delta T cells 

    Misiak, Alicja (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2015)
    γδ T cells are innate-like lymphocytes characterised by rapid activation following infection or tissue injury. They are enriched in the skin and epitheliae of various organs, where breach of the barrier is likely to occur. ...

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