RSS 1.0Biochemistry
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Biochemistry (Scholarly Publications)
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Biochemistry (Theses and Dissertations)
Recent Submissions
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An investigation into the physiological expression and function of mitochondrial uncoupling protein 1 in thymus
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2011)Our study confirms the presence of mitochondrial uncoupling protein 1 in thymus. Using laser scanning confocal microscopy, we showed the constitutive expression of UCP 1 in pure thymocytes. Using a primary peptide antibody ... -
A mechanism for bistability in glycosylation
(2018)Glycosyltransferases are a class of enzymes that catalyse the posttranslational modification of proteins to produce a large number of glycoconjugate acceptors from a limited number of nucleotide-sugar donors. The products ... -
Raising the bar in anticancer therapy:recent advances in, and perspectives on, telomerase inhibitors
(2019)Telomerase is a ribonucleic reverse transcriptase enzyme that uses an integral RNA component as a template to add tandem telomeric DNA repeats, TTAGGG, at the 3′ end of the chromosomes. 85–90% of human tumors and their ... -
Competition for nutrients; an emerging role in controlling immune responses
(2019)Changes in cellular metabolism are associated with the activation of diverse immune subsets. These changes are fuelled by nutrients including glucose, amino acids and fatty acids, and are closely linked to immune cell fate ... -
Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation
(2019)Metabolic pathways that regulate T-cell function show promise as therapeutic targets in diverse diseases. Here, we show that at rest cultured human effector memory and central memory CD4+ T-cells have elevated levels of ...
