• 

  Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21 

  Sheedy, Frederick; Keane, Joseph; Corr, Sinead; Lavelle, Edward (2020)

  Increased glycolytic metabolism recently emerged as an essential process driving host defense against Mycobacterium tuberculosis (Mtb), but little is known about how this process is regulated during infection. Here, we ...
• 

  Technological Approaches for Improving Vaccination Compliance and Coverage 

  Lavelle, Edward (2020)

  Vaccination has been well recognised as a critically important tool in preventing infectious disease, yet incomplete immunisation coverage remains a major obstacle to achieving disease control and eradication. As medical ...
• 

  Modulation of immune responses using adjuvants to facilitate therapeutic vaccination 

  Lavelle, Edward (2020)

  Therapeutic vaccination offers great promise as an intervention for a diversity of infectious and non-infectious conditions. Given that most chronic health conditions are thought to have an immune component, vaccination ...
• 

  Editorial: Challenges in Vaccinology 

  Lavelle, Edward (2020)

  The COVID19 pandemic has focused minds as rarely before on the vital contribution of vaccines to modern life. In addition to issues related to antigen identification, vaccine adjuvants, vectors and formulations, knowledge ...
• 

  Prevention and treatment of COVID-19 disease by controlled modulation of innate immunity 

  Lavelle, Edward (2020)

  The recent outbreak of coronavirus disease 2019 (COVID‐19), triggered by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) poses an enormous threat to global public health and economies. Human coronaviruses ...

View more