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Increased Population Risk of AIP-related Acromegaly and Gigantism in Ireland
(2016)The aryl hydrocarbon receptor interacting protein (AIP) founder mutation R304* (or p.R304*; NM_003977.3:c.910C>T, p.Arg304Ter) identified in Northern Ireland (NI) predisposes to acromegaly/gigantism; its population health ... -
Dysbiosis of salivary microbiota in inflammatory bowel disease and its association with oral immunological biomarkers.
(2014)Analysis of microbiota in various biological and environmental samples under a variety of conditions has recently become more practical due to remarkable advances in next-generation sequencing. Changes leading to specific ... -
Crohn's disease risk alleles on the NOD2 locus have been maintained by natural selection on standing variation.
(2012)Risk alleles for complex diseases are widely spread throughout human populations. However, little is known about the geographic distribution and frequencies of risk alleles, which may contribute to differences in disease ... -
Unequal rates of Y chromosome gene divergence during speciation of the family Ursidae.
(2008)Evolution of the bear family Ursidae is well investigated in terms of morphological, paleontological, and genetic features. However, several phylogenetic ambiguities occur within the subfamily Ursinae (the family Ursidae ...
