Academic/Research Units within this Academic/Research Unit

Recent Submissions

  • Factors influencing the induction of immune responses with DNA vaccines 

    Daly, Lyn M. (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2002)
    Compared with any other medical discovery vaccines have prevented more deaths and suffering. Emergence of novel pathogens accentuates the requisite for ongoing development and improvement of traditional vaccination strategies. ...
  • An investigation into the expression and physiological function of mitochondrial uncoupling proteins 

    Carroll, Audrey (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2004)
    Our study provides evidence that rat thymus contains a functioning mitochondrial uncoupling protein (UCP 1). Using reverse transcriptase-polymerase chain reaction (RT-PCR), we showed that rat thymus contains UCP 1 mRNA. ...
  • Analysis of the MAPK pathways, in silico and in vitro 

    Caffrey, Daniel Richard (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2002)
    This thesis takes a combined computational and experimental approach to study the MAPK pathways. These proteins were chosen as they are highly conserved in both sequence and function across all eukaryotes. An evolutionary ...
  • Local cellular and humoral immunity to Bordetella pertussis 

    Byrne, Patricia (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2004)
    The development of whole cell vaccine (Pw) and acellular pertussis vaccines (Pa) has had a huge impact on the incidence of whooping cough worldwide. The traditional Pw had high protective efficacy, but were associated with ...
  • Modulation of the inflammatory response by taurine and its structural analogue, HEPES 

    Brennan, Cara (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2000)
    Activated neutrophils (PMNs) have been implicated in the production of tissue injury in inflammatory-bowel disease (IBD) through release of proinflammatory mediaters during respiratory burst activity. Taurine, the most ...

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