Browsing Biochemistry (Scholarly Publications) by Title
Now showing items 216-235 of 725
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Facts and recommendations about total homocysteine determinations: an expert opinion
(American Association for Clinical Chemistry, 2004)Background: Measurement of plasma total homocysteine has become common as new methods have been introduced. A wide range of disorders are associated with increased concentrations of total homocysteine. The purpose of this ... -
Fas/CD95-Induced Chemokines Can Serve as "Find-Me" Signals for Apoptotic Cells.
(2013)Apoptosis is commonly thought to represent an immunologically silent or even anti-inflammatory mode of cell death, resulting in cell clearance in the absence of explicit activation of the immune system. However, here ... -
Fasciola hepatica suppresses a protective Th1 response against Bordetella pertussis
(The American Society for Microbiology, 1999)Fasciolosis, like other helminth infections, is associated with the induction of T-cell responses polarized to the Th2 subtype. Respiratory infection with Bordetella pertussis or immunization with a pertussis whole-cell ... -
A fast, simple and robust protocol for growing crystals in the lipidic cubic phase
(2012)A simple and inexpensive protocol for producing crystals in the sticky and viscous mesophase used for membrane protein crystallization by the in meso method is described. It provides crystals that appear within 15–30 min ... -
FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation.
(2014)Birt-Hogg-Dubé (BHD) syndrome is a rare autosomal dominant condition caused by mutations in the FLCN gene and characterized by benign hair follicle tumors, pneumothorax, and renal cancer. Folliculin (FLCN), the protein ... -
Folate/homocysteine phenotypes and MTHFR 677C>T genotypes are associated with serum levels of monocyte chemoattractant protein-1.
(Elsevier, 2009)Monocyte chemoattractant protein-1 (MCP-1) is a chemokine that recruits monocytes into the subendothelial cell layer in atherosclerotic lesions. Elevated homocysteine (hyperhomocysteinemia), which is usually associated ... -
Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation
(2021)Fructose intake has increased substantially throughout the developed world and is associated with obesity, type 2 diabetes and non-alcoholic fatty liver disease. Currently, our understanding of the metabolic and mechanistic ... -
Functional characterisation of the regulation of CAAT enhancer binding protein alpha by GSK-3 phosphorylation of Threonines 222/226
(BioMed Central, 2006)BACKGROUND: Glycogen Synthase Kinase-3 (GSK3) activity is repressed following insulin treatment of cells. Pharmacological inhibition of GSK3 mimics the effect of insulin on Phosphoenolpyruvate Carboxykinase (PEPCK), ... -
Functional Group and Substructure Searching as a Tool in Metabolomics
(2008)Background: A direct link between the names and structures of compounds and the functional groups contained within them is important, not only because biochemists frequently rely on literature that uses a free-text format ... -
A functional variant in MAL/TIRAP and protection against invasive pneumococcal disease, bacteraemia, malaria and tuberculosis
(2007)Toll-like receptors (TLRs) and members of their signaling pathway are important in the initiation of the innate immune response to a wide variety of pathogens1, 2, 3. The adaptor protein Mal (also known as TIRAP), encoded ... -
Galactosyltransferase 4 is a major control point for glycan branching in N-linked glycosylation
(2014)Protein N-glycosylation is a common post-translational modification that produces a complex array of branched glycan structures. The levels of branching, or antennarity, give rise to differential biological activities for ... -
Gating topology of the proton-coupled oligopeptide symporters
(2015)Peptide transport is the main route through which the body absorbs and retains dietary protein and hence plays an important role in human physiology (Steinhardt and Adibi, 1986). The combined action of acid hydrolysis in ... -
Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults
(American Society of Hematology, 2003)A modestly elevated total plasma homocysteine concentration (tHcy) is generally accepted as an independent and graded risk factor for various pathologies, including vascular diseases, neural tube defects, Alzheimer disease, ... -
Genome-Wide Association Analysis of Avian Resistance to Campylobacter jejuni Colonization Identifies Risk Locus Spanning the CDH13 Gene
(2013)The enteropathogen Campylobacter jejuni is a major worldwide health and economic burden, being one of the leading causes of bacterial gastroenteritis and commonly linked to postinfectious onset of autoimmune disease. ... -
Genome-wide transcriptional profiling of peripheral blood leukocytes from cattle infected with Mycobacterium bovis reveals suppression of host immune genes
(2011)Background: Mycobacterium bovis is the causative agent of bovine tuberculosis (BTB), a pathological infection with significant economic impact. Recent studies have highlighted the role of functional genomics to better ... -
Genotype variation at the MSTN locus is associated with skeletal muscle Coenzyme Q level in untrained Thoroughbred horses.
(2019)In the finely-tuned athletic species of Thoroughbred horses, polymorphisms (Intro 1 SNP g.66493737C>T and SINE insertion 227bp in promoter) in the myostatin gene (MSTN), a pronounced inhibitor of skeletal muscle growth, ... -
Gliadin antibody detection in gluten enteropathy.
(1986)Circulating antigliadin antibody has been described in patients with gluten enteropathy although the prevalence varies in different studies. It has been suggested that the investigation for antigliadin antibody might be ...