Browsing Biochemistry (Theses and Dissertations) by Sponsor "Health Research Board (HRB)"

Sort by: Order: Results:

Now showing items 1-3 of 3

  • Exploration of a novel class of HO-1 inducers as potential therapeutics for inflammatory disease 

    Fitzgerald, Hannah (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2022)
    Autoimmune and inflammatory diseases such as rheumatoid arthritis (RA), multiple sclerosis (MS), psoriasis, and inflammatory bowel disease (IBD) are characterised by excessive and uncontrolled inflammation. Most of these ...

  • Harnessing the therapeutic properties of the Heme Oxygenase system 

    CAMPBELL, NICOLE KAREN (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2018)
    The stress response enzyme, Heme Oxygenase 1 (HO-1), has been identified as an important immunomodulator which is highly upregulated in response to cellular stress and inflammation. HO-1 catalyses the conversion of free ...

  • HUMAN HEPATIC NATURAL KILLER CELLS IN HEALTH AND MALIGNANCY 

    HARMON, CATHAL (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2018)
    The adult human liver is described as an immunologically tolerogenic organ, maintaining a homeostatic environment while bombarded by dietary antigens, microbial products and metabolic by-products. The liver is also a site ...