Recent Submissions

  • An immunomodulatory role for indole-3-pyruvate, an excreted metabolite of the parasite Trypanosoma Brucei 

    CORCORAN, SARAH ELIZABETH (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2017)
    Human African trypanosomiasis, more commonly known as sleeping sickness, is one of the world's neglected diseases. Trypanosoma brucei, an extracellular parasitic protozoan of the genus Trypanosoma, is the causative agent. ...
  • Metabolic flux control of mitochondrial dynamics in cancer cells 

    MCGARRIGLE, RYAN (Trinity College Dublin. School of Engineering. Discipline of Electronic & Elect. Engineering, 2017)
  • The immunomodulatory effects of NOD1 activation 

    Kelly, Patrick Joseph (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2014)
    NOD1 and NOD2 are cytosolic pathogen recognition receptors (PRRs) which detect peptidoglycan derivatives and contribute to the host defence during bacterial infection. Transgenic mice lacking NOD1 or NOD2 are susceptible ...
  • Genetic variation in bulls divergent for fertility 

    WHISTON, RONAN (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2017)
    Bovine fertility remains a critical issue underpinning the sustainability of the agricultural sector. Since the realisation of an unfavourable relationship between fertility and production traits in cattle, methods to ...
  • Regulation of bovine beta-defensin expression 

    Barry-Reidy, Anne (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2017)
    Beta-defensins are a class of host defence peptides with antibacterial, antiviral and immunomodulatory roles. The bovine genome contains up to 57 putative beta-defensin genes in four syntenic clusters on different chromosomes. ...

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