Recent Submissions

  • Innate resistance to hepatitis C virus infection in the Irish anti-D cohort 

    Sugrue, Jamie Alan (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2022)
    Even within homogenous populations, outcome following exposure to a virus can vary substantially. This continuum of infection outcome spans viral resistance, spontaneous resolution and chronic infection, with further ...
  • A study of bioenergetics and mitochondrial function in Cytotoxic T cell subsets 

    Davis, Gavin (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2022)
    CD8 T cell fate and function have been linked to specific metabolic programs. T effector (T eff) and T memory (T mem) cells engage mitochondrial metabolism to different extents, as recognised by stark differences in ...
  • The role of dietary fat in anti-tumour immunity 

    Prendeville, Hannah Catherine (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2022)
    Obesity increases the risk of many cancers and impairs immunosurveillance. However, little is known about whether the type of dietary fat affects tumour growth and anti-tumour immune responses. Here, we show that a ...
  • Investigating a role for members of the respiratory tract microbiota in Th17 cell pathogenicity and CNS autoimmunity 

    Mannion, Jenny (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2022)
    The respiratory tract is home to a diverse microbial community whose influence on local and systemic immune responses is only beginning to be appreciated. Increasing reports have linked the airways with the trafficking ...
  • Gone or Misplaced?: Investigation of Memory Engrams Across Development 

    Power, Sarah (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2022)
    All humans experience amnesia. While about 30% of adults who live to be over 65 will suffer from dementia, 100% of the human population experiences infantile amnesia, which is the loss of memories formed in early childhood ...

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