Recent Submissions

  • HAMLET and synthetic derivatives as pre-operative agents in the treatment of oral and oesophageal cancer 

    Ghanim, Magda (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)
    Oral and oesophageal cancers are aggressive tumours that are frequently diagnosed late, with high morbidity, mortality, and difficulties in surgical and therapeutic intervention. Novel imaging probes could assist in early ...
  • The immunomodulatory properties of L-rhamnose 

    LUNDAHL, MIMMI LOUISE (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)
    L-Rhamnose is a non-mammalian monosaccharide ubiquitously found on the surface of both commensal and pathogenic bacteria. Previous publications had identified that L-rhamnose-rich Mycobacterium tuberculosis glycolipids, ...
  • Inflammasome Involvement in Barrett's and Oesophageal Adenocarcinoma 

    BARBER, GILLIAN LOUISE (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)
    Barrett's oesophagus is an inflammatory condition and a neoplastic precursor to oesophageal adenocarcinoma (OAC). Inflammasome signalling pathways contribute to acute and chronic inflammation, and can be enhanced by obesity. ...
  • Characterisation of the immune response to calcium phosphate particulates; implications for osteoarthritis and bone tissue engineering 

    MAHON, OLWYN (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)
    Early trauma, resulting in focal areas of cartilage damage with injury to the underlying subchondral bone (osteochondral damage) often progresses to arthritis. These so called osteochondral defects (OCDs) can arise from ...
  • A novel role of SOCS-4 and SOCS-5 in cytokine signalling 

    ALMOHAMMADI, DANIAH HAMEED (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)
    The immune system is propagated by cytokines and their intracellular signal transduction. To ensure an appropriate immune response, these signalling pathways are tightly controlled. One such regulatory mechanism is the ...

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