Recent Submissions

  • NK1.1 receptor ligation or tumour interactions prime NK cells for IL2-mediated metabolic and functional responses 

    KEDIA MEHTA, NIDHI (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2019)
    Natural Killer (NK) cells undergo a distinct metabolic response following cytokine stimulation, which involves increased rates of glycolysis and oxidative phosphorylation (OxPhos). This metabolic response is essential for ...
  • The role of amines in paraganglioma, neuroblastoma and carcinoid diagnosis 

    Tormey, William P. (Trinity College (Dublin, Ireland). Department of Chemical Pathology, 2000)
    The role of urinary noradrenaline, adrenaline, dopamine, 4-hydroxy-3-methoxy-mandelic acid (HMMA) and homovanillic acid (HVA) in the diagnosis of paraganglioma especially phaeochromocytoma and in neuroblastoma is investigated. ...
  • Structure-function and pharmacological studies on the mammalian serotonin transporter 

    Scanlon, Siobhán Mary (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2002)
    In Pichia pastoris, the existing membrane ergosterol was replaced by cholesterol in an attempt to improve folding of the low affinity heterologously expressed rat serotonin transporter, as judged by means of radioligand ...
  • The alcohol dehydrogenases of Bacillus stearothermophilus 

    Robinson, Glynis A. (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2001)
    A 1.5-kb fragment of Bacillus stearothermophilus DSM 2334 DNA was subcloned into pUC18, and the nucleotide sequence was determined. The fragment contained a complete open reading frame that encoded a 339-residue amino-acid ...
  • Semicarbazide-sensitive amine oxidase & 5-HT in dental pulp 

    O'Sullivan, Michael (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2000)
    This thesis investigated the behavior of semicarbazide sensitive amine oxidase (SSAO) and the unique activity that it possesses towards 5-hydroxytryptamine (5-HT) in various dental pulp tissues. This summary presents the ...

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