Browsing Biochemistry (Theses and Dissertations) by Subject "antiviral"

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    • Antiviral activity of human hepatocytes and its regulation by cellular antioxidant systems 

      Sularea, Vasile Mihai (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)
      Although several antiviral strategies have been developed in the last decade, hepatotropic viruses are still a significant public health burden, with more than 300 million people being affected worldwide. Hepatocytes, the ...

    • Investigating the Signalling and Function of C5aR2 

      Wright, Oliver (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)
      Complement component 5a receptor 2 (C5aR2) is an enigmatic receptor for anaphylatoxin C5a. It was initially thought to be a decoy receptor, competitively binding to C5a to negatively regulate C5aR1 signalling. However, ...