Browsing Biochemistry (Theses and Dissertations) by Subject "Immunology, Ph.D."
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Systemic and local immune responses associated with subclinical endometritis in the postpartum diary cow
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2014)Activation of local innate immune mechanisms by postpartum bacterial contamination of the uterus occurs in all cows and approximately 30% develop endometritis associated with persistent bacterial infection, inflammation ... -
The characterisation of Human Vδ3 T cells
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2014)Human γδ T cells expressing the Vδ3 TCR make up a minor lymphocyte subset in blood but are enriched in liver and in patients with some chronic viral infections and leukemias. We analysed the frequencies, phenotypes, ... -
The pathogenicity and regulation of CD161⁺Th17 lineage cells in rheumatoid arthritis
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2015)Pathogenic Th17 cells, which produce their signature cytokine IL-17, play a key role in autoimmune diseases such as rheumatoid arthritis (RA) and therefore, have been the target of recently developed therapeutics. On the ...