Browsing Biochemistry (Theses and Dissertations) by Author "Varghese, Sreeja"
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The Queuine-Transfer RNA Pathway as a novel drug mechanism to treat Multiple Sclerosis
Varghese, Sreeja (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2012)Queuine is a pyrrolopyrimidine molecule that is irreversibly incorporated into the anticodon loop of transfer RNA (tRNA) for the amino acids Asparagine, Aspartate, Tyrosine and Histidine. Only bacteria synthesize queuine, ...