The inflammatory degenerative continuum of HIV related cognitive impairment
Citation:
Patricia Helena McNamara, 'The inflammatory degenerative continuum of HIV related cognitive impairment', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2015, pp 529Download Item:
Abstract:
This thesis is the result of three years of research from January 2011 to December
2013 examining the role of cognition in HIV infection in an Irish specialist HIV service.
This had not previously been examined in Ireland. Four studies were undertaken which
were all linked. The first examined the prevalence of a positive screen for cognitive
impairment. The second examined the cognitive profile of HAND in Ireland in the post
highly active anti-retroviral therapy era. The third study investigated the magnetic
resonance imaging (MRI) features of HAND with voxel based morphometry (VBM) and
diffusion tensor imaging (DTI). The final study explored the immunological,
inflammatory and degenerative biomarkers of HAND in cerebrospinal fluid. All of the
studies were cross-sectional in nature.
Author: McNamara, Patricia Helena
Advisor:
Bergin, ColmQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical MedicineNote:
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