Sort by: Order: Results:

Now showing items 1-20 of 179

  • Pain sensitivity in general practice 

    Smith, Robert (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 1957)
    This investigation was carried out during the ordinary routine work of general practice. It consisted of applying a simple test and considering the result in relation to the general clinical picture. The test is performed ...
  • A study of congenital malformation in new born in Lagos, Nigeria 

    Lesi, Folorunso Ebun Akinboye (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 1969)
    Summary: Some historical notes of the knowledge and beliefs regarding congenital malformations were reviewed. Based on a survey carried out at the Lagos Island Maternity Hospital, Nigeria, amongst 16,720 consecutive ...
  • Particulate air pollution and mortality in Dublin 1980-1996 

    Goodman, Patrick Gerard (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2000)
    Air pollution in Dublin was studied for the period from 1980 to 1996. The factors which contribute to air pollution were investigated, and the nature of particulate air pollution is discussed. The trends in air pollution, ...
  • The nutritional status of hospital patients and healthy elderly living in the community 

    Corish, Clare Anne (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2000)
    Protein-energy undernutrition is known to occur in patients on admission to hospital. In a prospective study of 594 sequential hospital admissions, we assessed the prevalence of undernutrition among patients on admission ...
  • Nutritional aspects of trans unsaturated fatty acids 

    Cantwell, Mary Margaret (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2000)
    Dietary trans unsaturated fatty acids from hydrogenated vegetable and fish oils have been shown to raise plasma low density lipoprotein cholesterol and lower high density lipoprotein cholesterol levels at 10%, 6% and 3% ...
  • Tools and techniques for improving the assessment of exposure to food chemicals 

    Lambe, Joyce (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2000)
    Exposure assessments are an integral part of risk assessment and are essential for protecting consumer health and factilitating international trade. The aim of this thesis was to explore the potential usefulness of a number ...
  • Nutritional and metabolic aspects of n-3 polyunsaturated fatty acids in health and disease 

    Tully, Anne-Marie (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2000)
    The health benefits of fish oils, rich in the n-3 polyunsaturated fatty acids (PUFA) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are multi-faceted, spanning a number of human systems, including the cardiovascular, ...
  • Enternal nutrition in the community setting 

    McNamara, Edel (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2001)
    The practice of tube feeding patients outside the acute hospital setting has existed in Ireland for over a decade. Anecdotal evidence (mainly from hospital dietitians) suggested that the care services for these patients ...
  • Methodological issues in risk assessment of human exposure to artificial sweeteners in food 

    Cullen, Muireann Gearóidín (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2001)
    The primary aim of this thesis is in estimating food chemical intakes with a specific interest in the area of intense sweeteners. To date all studies of intense sweeteners have been extremely detailed both in the estimate ...
  • Molecular aspects of human lipid metabolism 

    Black, Irene Lucy (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2001)
    The postprandial lipaemic response refers to the changes in lipid and lipoprotein concentrations after consumption of a meal containing more than 15g of long-chain fatty acids. The magnitude and duration of the response ...
  • Evaluation of Triple helix-forming Oligonucleotides as modulators of transcriptional initiation in erbB-2/HER-2-positive breast cancer : an anti-tumour approach 

    Dolan, Colette (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2001)
    Research over the last several decades has made tremendous strides in the identification of the components of the human genome. Genetic information is expressed by translation of DNA into functional proteins through the ...
  • The study of periodicity of eating & public health nutrition issues 

    Harrington, Karen E. (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2001)
    This thesis set out to provide an objective understanding of periodicity of eating in a group of free- living adults, by determining the temporal pattern of nutrient intake during eating occasions throughout the day. A ...
  • Postprandial lipoprotein metabolism in diabetes 

    Phillips, Catherine Mary (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2001)
    Cardiovascular disease is up to four times greater in patients with Type 2 diabetes compared with nonnoglycaemic individuals (Pyorala et al., 1987; Laakso and Lehto 1997). Abnormalities in lipid metabolism may, in part, ...
  • The folate catabolic process, its implications for folate requirement in humans and its antibacterial drug function 

    Quinlivan, Eoin P. (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2001)
    The one-carbon cycle, of which folate is the predominant constituent, is a major carrier of one-carbon units for biochemical synthesis, and is thought to be the sole mechanism of methyl-group transfer. It is involved both ...
  • Dietary and genetic factors affecting the cholesteryl ester transfer protein and lipoprotein metabolism 

    Noone, Enda (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2001)
    The cholesteryl ester transfer protein (CETP) plays an inherent role in the redistribution of neutral lipids between high density lipoproteins (HDL) and very low density lipoproteins (VLDL) and low density lipoproteins ...
  • Folic acid fortification of flour : determination of the level that gives rise to unmetabolised folic acid in serum 

    Sweeney, Mary Rose (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2001)
    To prevent neural tube defects the Food and Drug Administration (FDA) implemented mandatory folic acid fortification o f all flour milled in the USA at a level 140μg/100g. The Centers for Disease Control (CDC) have proposed ...
  • Dietary fatty acids and diabetes mellitus : effect on postprandial lipoproteins and apolipoproteins 

    Madigan, Claire (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2002)
    This thesis explores the relative merits of dietary polyunsaturated and monounsaturated fat in reducing the postprandial dyslipidaemia which is associated with diabetes. Of particular interest are the apolipoproteins which ...
  • Migration of lymphoma and lymphocyte T cells on flat and grooved microfabricated surfaces : comparative analysis of peripheral blood T lymphocytes and lymphoma human T cell line HUT78 

    Prino-Mello, Adriele (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2003)
    Normal and malignant cell migration represents a fundamentally important process involved in tissue growth and development, inflammation and cancer metastasis. Leukocyte trafficking from blood into tissues is currently ...
  • Transcriptional response to prolonged acid exposure and genetic divergence in Helicobacter pylor 

    Dong, Quanjiang (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2003)
    Helicobacter pylori infection is strongly associated with gastritis, peptic ulcer and gastric adenocarcinoma. Molecular mechanisms involved in H. pylori adaptation and clinical consequences of infection are unclear. This ...
  • The Tumour Necrosis Factor region in coeliac disease 

    Daly, Jacqueline S. (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2003)
    Coeliac disease is a disease of the small intestine, characterised by villous atrophy and crypt hyperplasia. The disease can be defined as an intolerance in genetically susceptible individuals to certain storage proteins ...