Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children
Citation:
Lewinsohn David M, Leonard Michael K, LoBue Philip A, Cohn David L, Daley Charles L, Desmond Ed, Keane Joseph, Lewinsohn Deborah A, Loeffler Ann M, Mazurek Gerald H, Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children, Clinical Infectious Diseases, 2017, 64, 2, e1–e33Download Item:
Abstract:
Background: Individuals infected with Mycobacterium tuberculosis (Mtb) may develop symptoms and signs of disease (tuberculosis disease) or may have no clinical evidence of disease (latent tuberculosis infection [LTBI]). Tuberculosis disease is a leading cause of infectious disease morbidity and mortality worldwide, yet many questions related to its diagnosis remain. Methods: A task force supported by the American Thoracic Society, Centers for Disease Control and Prevention, and Infectious Diseases Society of America searched, selected, and synthesized relevant evidence. The evidence was then used as the basis for recommendations about the diagnosis of tuberculosis disease and LTBI in adults and children. The recommendations were formulated, written, and graded using the Grading, Recommendations, Assessment, Development and Evaluation (GRADE) approach.Results.Twenty-three evidence-based recommendations about diagnostic testing for latent tuberculosis infection, pulmonary tuberculosis, and extrapulmonary tuberculosis are provided. Six of the recommendations are strong, whereas the remaining 17 are conditional. Conclusions: These guidelines are not intended to impose a standard of care. They provide the basis for rational decisions in the diagnosis of tuberculosis in the context of the existing evidence. No guidelines can take into account all of the often compelling unique individual clinical circumstances.
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http://people.tcd.ie/josephmkDescription:
PUBLISHED
Author: Keane, Joseph
Publisher:
Oxford University PressType of material:
Journal ArticleCollections
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Clinical Infectious Diseases;Availability:
Full text availableKeywords:
Mycobacterium tuberculosis (Mtb), Latent tuberculosis infection (LTBI), Grading, Recommendations, Assessment, Development, and Evaluation (GRADE) approach, Infectious disease morbidityDOI:
https://doi.org/10.1093/cid/ciw694ISSN:
1058-4838Metadata
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