Characterisation of SdrC, SdrD and SdrE from the serine-aspartate repeat family of Staphylococcus auerus
Citation:
Louise Marie O'Brien, 'Characterisation of SdrC, SdrD and SdrE from the serine-aspartate repeat family of Staphylococcus auerus', [thesis], Trinity College (Dublin, Ireland). Department of Microbiology, 2001, pp 324Download Item:
O'Brien TCD THESIS 6264 Characterisation of.pdf (PDF) 187.5Mb
Abstract:
Staphylococcus aureus is an important human pathogen. The ability of S. aureus
to initiate infection is attributed at least partly to the expression of cell wall-associated
proteins known as MSCRAMMs (microbial surface components recognising adhesive
matrix molecules). MSCRAMMs mediate the adherence of S. aureus to a variety of host
ligands such as fibrinogen, fibronectin, collagen, elastin, thrombospondin, vitronectin,
laminin, von Willebrand factor and mucin. This allows the bacterium to establish
infections at various tissue sites and on biomaterial implants that have become coated
with host proteins.
Author: O'Brien, Louise Marie
Advisor:
Foster, TimQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). Department of MicrobiologyNote:
TARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.iePrint thesis water damaged as a result of the Berkeley Library Podium flood 25/10/2011
Type of material:
thesisAvailability:
Full text availableKeywords:
Microbiology, Ph.D., Ph.D. Trinity College DublinLicences: