Genomic characterisation and comparative proteome analysis of Helicobacter pylori related gastroduodenal pathologies
Citation:
Abdurrazag Taher Nami, 'Genomic characterisation and comparative proteome analysis of Helicobacter pylori related gastroduodenal pathologies', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2009, pp 266Download Item:
Abstract:
The Gram-negative bacterium Helicobacter pylori is a gastric pathogen that chronically infects more than half the world’s population. H. pylori infection induces various upper gastro- duodenal diseases, and there is a marked difference in clinical outcomes due to bacterial infection among different regions in the world, H. pylori infection causes many perturbations of gastric structure and function. The nature and extent of the perturbation relates in part to the virulence of the organism, to the host’s genetically determined response to the presence of the infection, and environmental factors that might up or down regulate the interactions. This study aimed to recruit a patient population including patients with intestinal metaplasia as well as peptic ulcer and chronic gastritis patients to find genetic markers of H. pylori related gastro duodenal diseases.
Author: Nami, Abdurrazag Taher
Advisor:
O'Morain, ColmQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical MedicineNote:
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