The analysis of the modulatory effect of rosiglitazone on glial cells in vitro and in vivo
Citation:
Brian Deighan, 'The analysis of the modulatory effect of rosiglitazone on glial cells in vitro and in vivo', [thesis], Trinity College (Dublin, Ireland). Department of Physiology, 2010, pp 326Download Item:
Abstract:
Microglial activation is believed to play an important role in the pathogenesis of neurodegenerative and neuroinflammatory diseases. This study focussed on assessing the role of rosiglitazone as an anti-inflammatory agent and analysis was carried out to evaluate its effect in vitro and in vivo. The specific mechanism by which rosiglitazone might exert its effect was investigated and its effect on different glial cell types was also assessed.
Author: Deighan, Brian
Advisor:
Lynch, MarinaQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). Department of PhysiologyNote:
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Full text availableKeywords:
Physiology, Ph.D., Ph.D. Trinity College DublinMetadata
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