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  The signalling and function of EB12 in the central nervous system 

  Rutkowska, Aleksandra (Trinity College (Dublin, Ireland). Department of Physiology, 2014)

  The four major brain-specific cell types in the brain are; (i) neurons, which transmit and process information via electrical signals, (ii) oligodendrocytes, which insulate neuronal axons with fatty sheets called myelin ...
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  The modulation of S1P receptor signalling and demyelination 

  Pritchard, Adam (Trinity College (Dublin, Ireland). Department of Physiology, 2014)

  Sphingosine 1-phosphate receptors are a family of G-protein coupled receptors (GPCRs) that consists of five subtypes (S1PR1-5). These receptors have emerged as therapeutic targets in multiple sclerosis (MS) due to the ...
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  Interactions between endocannabinoids and neurotrophins in adult neurogenesis : implications for spatial memory 

  Prenderville, Jack (Trinity College (Dublin, Ireland). Department of Physiology, 2014)

  The cellular mechanisms underlying learning and memory have yet to be fully elucidated. Over the past fifteen years there has been a dramatic increase in the study of adult neurogenesis; a process in which neurons are ...
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  Investigating the role of inflammation in schizophrenia 

  O'Connell, Kara E. (Trinity College (Dublin, Ireland). Department of Physiology, 2013)

  Schizophrenia is a psychiatric illness that has more recently been described as a neurodevelopment disorder. The cause of this disorder is currently unknown and likely involves both genetic and environmental factors. Several ...
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  Rodent models of immunologically induced-depression and anxiety related behaviour and associated biomarkers 

  McGuinness, Barry (Trinity College (Dublin, Ireland). Department of Physiology, 2014)

  A series of rodent animal models of immune activation were assessed to develop an understanding of interactions between the immune system and brain leading to changes in behaviour and the determination of biomarkers of ...

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