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dc.contributor.authorFARES, MARIO ALI
dc.date.accessioned2013-09-02T13:35:38Z
dc.date.available2013-09-02T13:35:38Z
dc.date.issued2009
dc.date.submitted2009en
dc.identifier.citationCommins, J., Toft, C., Fares, M.A., Computational Biology Methods and Their Application to the Comparative Genomics of Endocellular Symbiotic Bacteria of Insects, Biological Procedures Online, 11, 2009, 52-78en
dc.identifier.otherY
dc.identifier.urihttp://hdl.handle.net/2262/67304
dc.descriptionPUBLISHEDen
dc.description.abstractComparative genomics has become a real tantalizing challenge in the postgenomic era. This fact has been mostly magnified by the plethora of new genomes becoming available in a daily bases. The overwhelming list of new genomes to compare has pushed the field of bioinformatics and computational biology forward toward the design and development of methods capable of identifying patterns in a sea of swamping data noise. Despite many advances made in such endeavor, the ever-lasting annoying exceptions to the general patterns remain to pose difficulties in generalizing methods for comparative genomics. In this review, we discuss the different tools devised to undertake the challenge of comparative genomics and some of the exceptions that compromise the generality of s uch methods. We focus on endosymbiotic bacteria of insects because of their genomic dynamics peculiarities when compared to free-living organismsen
dc.format.extent52-78en
dc.language.isoenen
dc.relation.ispartofseriesBiological Procedures Online;
dc.relation.ispartofseries11;
dc.rightsYen
dc.subjectComparative genomics has become a real tantalizing challenge in the postgenomic era. This fact has been mostly magnified by the plethora of new genomes becoming available in a daily bases. The overwhelming list of new genomes to compare has pushed the field of bioinformatics and computational biology forward toward the design and development of methods capable of identifying patterns in a sea of swamping data noise. Despite many advances made in such endeavor, the ever-lasting annoying exceptions to the general patterns remain to pose difficulties in generalizing methods for comparative genomics. In this review, we discuss the different tools devised to undertake the challenge of comparative genomics and some of the exceptions that compromise the generality of s uch methods. We focus on endosymbiotic bacteria of insects because of their genomic dynamics peculiarities when compared to free-living organismsen
dc.subject.lcshComparative genomics has become a real tantalizing challenge in the postgenomic era. This fact has been mostly magnified by the plethora of new genomes becoming available in a daily bases. The overwhelming list of new genomes to compare has pushed the field of bioinformatics and computational biology forward toward the design and development of methods capable of identifying patterns in a sea of swamping data noise. Despite many advances made in such endeavor, the ever-lasting annoying exceptions to the general patterns remain to pose difficulties in generalizing methods for comparative genomics. In this review, we discuss the different tools devised to undertake the challenge of comparative genomics and some of the exceptions that compromise the generality of s uch methods. We focus on endosymbiotic bacteria of insects because of their genomic dynamics peculiarities when compared to free-living organismsen
dc.titleComputational Biology Methods and Their Application to the Comparative Genomics of Endocellular Symbiotic Bacteria of Insectsen
dc.typeJournal Articleen
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/faresm
dc.identifier.rssinternalid87385


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