Browsing Genetics (Scholarly Publications) by Author "HOKAMP, KARSTEN"
Now showing items 1-9 of 9
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Cell envelope gene expression in phosphate-limited Bacillus subtilis cells.
BOTELLA, ERIC; DEVINE, KEVIN; HOKAMP, KARSTEN (2011)The high phosphate content of Bacillus subtilis cell walls dictates that cell wall metabolism is an important feature of the PhoPR-mediated phosphate limitation response. Here we report the expression profiles of ... -
CHD5 is required for neurogenesis and has a dual role in facilitating gene expression and polycomb gene repression
STREUBEL, GUNDULA; HOKAMP, KARSTEN (2013)The chromatin remodeler CHD5 is expressed in neu- ral tissue and is frequently deleted in aggressive neuroblastoma.Verylittleisknownaboutthefunction of CHD5 in the nervous system or its mechanism of action. Here we ... -
Compensatory evolution of gene regulation in response to stress by Escherichia coli lacking RpoS.
DORMAN, CHARLES JAMES; HOKAMP, KARSTEN (2009)The RpoS sigma factor protein of Escherichia coli RNA polymerase is the master transcriptional regulator of physiological responses to a variety of stresses. This stress response comes at the expense of scavenging for ... -
The extracellular leucine-rich repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns.
MITCHELL, KEVIN; DOLAN, JACKIE; HOKAMP, KARSTEN; OKAFUJI, TATSUYA (2007)BACKGROUND: Leucine-rich repeats (LRRs) are highly versatile and evolvable protein-ligand interaction motifs found in a large number of proteins with diverse functions, including innate immunity and nervous system development. ... -
Global Gene Expression and Systems Biology Analysis of Bovine Monocyte-Derived Macrophages in Response to In Vitro Challenge with Mycobacterium bovis
HOKAMP, KARSTEN (2012)BACKGROUND: Mycobacterium bovis, the causative agent of bovine tuberculosis, is a major cause of mortality in global cattle populations. Macrophages are among the first cell types to encounter M. bovis following exposure ... -
An infection-relevant transcriptomic compendium for Salmonella enterica Serovar Typhimurium.
HOKAMP, KARSTEN; KROGER, CARSTEN (2013)Bacterial transcriptional networks consist of hundreds of transcription factors and thousands of promoters. However, the true complexity of transcription in a bacterial pathogen and the effect of the environments encountered ... -
A model system for studying the transcriptomic and physiological changes associated with mammalian host-adaptation by Leptospira interrogans serovar Copenhageni.
HOKAMP, KARSTEN (2014)Leptospirosis, an emerging zoonotic disease with worldwide distribution, is caused by spirochetes belonging to the genus Leptospira . More than 500,000 cases of severe leptospirosis are reported annually, with . 10% ... -
PubCrawler: keeping up comfortably with PubMed and GenBank
HOKAMP, KARSTEN; WOLFE, KENNETH (Oxford University Press, 2004)The free PubCrawler web service (http://www.pubcrawler.ie) has been operating for five years and so far has brought literature and sequence updates to over 22 000 users. It provides information on a personalized web page ... -
Whole-transcriptome, high-throughput RNA sequence analysis of the bovine macrophage response to Mycobacterium bovis infection in vitro
HOKAMP, KARSTEN (BioMed Central Ltd, 2013)Background Mycobacterium bovis, the causative agent of bovine tuberculosis, is an intracellular pathogen that can persist inside host macrophages during infection via a diverse range of mechanisms that subvert the host ...