Browsing Clinical Medicine (Scholarly Publications) by Sponsor "European Union Framework Programme 7 (FP7)"
Now showing items 1-6 of 6
-
An Exploratory Spatial Analysis of ALS Incidence in Ireland over 17.5 Years (1995 - July 2013)
(2014)Abstract Introduction There has been much interest in spatial analysis of ALS to identify potential environmental or genetically caused clusters of disease. Results to date have been inconclusive. The Irish ALS register ... -
Presymptomatic and longitudinal neuroimaging in neurodegeneration: from snapshots to motion picture - a systematic review
(2015)Background Recent quantitative neuroimaging studies have been successful in capturing phenotype and genotype-speci fi c changes in dementia syndromes, amyotrophic lateral sclerosis, Parkinson ’ s disease and other ... -
Pyruvate Kinase M2 Regulates Hif-1alfa Activity and IL-1? Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages.
(2015)TLR4-activated macrophages switch their metabolism from oxidative phosphorylation to glycolysis to rapidly provide for the high energy and biosynthetic demands of infection or injury response. Palsson-McDermott identify ... -
Survival Analysis of Irish Amyotrophic Lateral Sclerosis Patients Diagnosed from 1995 2010
(2013)Introduction: The Irish ALS register is a valuable resource for examining survival factors in Irish ALS patients. Cox regression has become the default tool for survival analysis, but recently new classes of flexible ... -
Towards a nanospecific approach for risk assessment.
(2016)In the current paper, a new strategy for risk assessment of nanomaterials is described, which builds upon previous project outcomes and is developed within the FP7 NANoREG project. NANoREG has the aim to develop, for the ... -
What does the ALSFRS-R really measure? A longitudinal and survival analysis of functional dimension subscores in amyotrophic lateral sclerosis
(2017)Introduction: ALSFRS-R is the most widely used functional rating system in ALS patients. However, heterogeneity in ALSFRS-R progression renders analysis challenging. We have explored the characteristics of total ALSFRS-R, ...