Browsing Clinical Medicine (Theses and Dissertations) by Author "Forde, James Christopher"
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The role of HIF-lalpha and hypoxia in the preferential response of prostate tumours to microtubule-targeting agents
Forde, James Christopher (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2010)Tumour hypoxia is emerging as a common feature of prostate tumours associated with poor prognosis mainly due to their resistance to chemo- radiotherapy regimes. The efficacy of microtubule-targeting agents (MTAs) has ...