Browsing Biochemistry (Scholarly Publications) by Subject "Ligand based drug design"
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Identification of Plasmepsin Inhibitors as Selective Antimalarial Agents using Ligand Based Drug Design
(Elsevier, 2011)We describe the application of Ligand Based Virtual Screening technologies towards the discovery of novel Plasmepsin (PM) inhibitors, a family of malarial parasitic aspartyl proteases. Pharmacophore queries were used to ...