Browsing Biochemistry (Scholarly Publications) by Author "O'Driscoll, Lorraine"
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2-Deoxy-D-Glucose inhibits aggressive triple-negative breast cancer cells by targeting glycolysis and the cancer stem cell phenotype
O'Driscoll, Lorraine; Porter, Richard (2019)Due to limited availability of pharmacological therapies, triple-negative breast cancer (TNBC) is the subtype with worst outcome. We hypothesised that 2-Deoxy-D-Glucose (2-DG), a glucose analogue, may hold potential as a ...