Browsing Biochemistry (Scholarly Publications) by Author "Lacey, Keenan A."
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Clumping factor B is an important virulence factor during Staphylococcus aureus skin infection and a promising vaccine target
Mc Loughlin, Rachel; Lacey, Keenan A.; Mulcahy, Michelle E.; Towell, Aisling M.; Geoghegan, Joan A. (2019)Staphylococcus aureus expresses a number of cell wall-anchored proteins that mediate adhesion and invasion of host cells and tissues and promote immune evasion, consequently contributing to the virulence of this organism. ... -
IL-10 Plays Opposing Roles during Staphylococcus aureus Systemic and Localized Infections.
Mc Loughlin, Rachel; Leech, John M.; Lacey, Keenan A.; Mulcahy, Michelle E.; Medina, Eva (2017)IL-10 is a potent anti-inflammatory mediator that plays a crucial role in limiting host immunopathology during bacterial infections by controlling effector T cell activation. Staphylococcus aureus has previously been shown ...