| dc.contributor.advisor | Foster, Timothy | |
| dc.contributor.author | Dorman, Charles James | |
| dc.date.accessioned | 2017-05-15T13:23:26Z | |
| dc.date.available | 2017-05-15T13:23:26Z | |
| dc.date.issued | 1985 | |
| dc.identifier.citation | Charles James Dorman, 'Analysis of the chloramphenicol resistance determinant of plasmid R26', [thesis], Trinity College (Dublin, Ireland). Department of Microbiology, 1985, pp 296 | |
| dc.identifier.other | THESIS 972 | |
| dc.identifier.uri | http://hdl.handle.net/2262/79996 | |
| dc.description.abstract | The Inc P-1 plasmid, R2B carries an inducible chloramphenicol resistance determinant, cml. This specifies low level chloramphenicol resistance (30 μg/ml] in Escherichia coli. The mechanism does not involve drug detoxification or ribosomal modification, but may involve a permeability barrier to drug uptake acting at the cytoplasmic membrane. Experiments described in this thesis show that cml also specifies resistance to some fluorinated derivatives of chloramphenicol. | |
| dc.format | 1 volume | |
| dc.language.iso | en | |
| dc.publisher | Trinity College (Dublin, Ireland). Department of Microbiology | |
| dc.relation.isversionof | http://stella.catalogue.tcd.ie/iii/encore/record/C__Rb12477373 | |
| dc.subject | Microbiology, Ph.D. | |
| dc.subject | Ph.D. Trinity College Dublin | |
| dc.title | Analysis of the chloramphenicol resistance determinant of plasmid R26 | |
| dc.type | thesis | |
| dc.type.supercollection | thesis_dissertations | |
| dc.type.supercollection | refereed_publications | |
| dc.type.qualificationlevel | Doctoral | |
| dc.type.qualificationname | Doctor of Philosophy (Ph.D.) | |
| dc.rights.ecaccessrights | openAccess | |
| dc.format.extentpagination | pp 296 | |
| dc.description.note | TARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie | |
