Academic/Research Units within this Academic/Research Unit

Recent Submissions

  • Insufficient Evidence for "Autism-Specific" Genes 

    Mitchell, Kevin; Challman, Thomas D.; Bernier, Raphael; Bourgeron, Thomas; Chung, Wendy K.; Constantino, John N.; Eichler, Evan E.; Jacquemont, Sebastien; Miller, David T.; Zoghbi, Huda Y.; Martin, Christa Lese; Ledbetter, David H. (2020)
    Despite evidence that deleterious variants in the same genes are implicated across multiple neurodevelopmental and neuropsychiatric disorders, there has been considerable interest in identifying genes that, when mutated, ...
  • Getting a gRIP on Flu by Casting the DAI 

    MARTIN, SEAMUS; Clancy, Danielle M. (2016)
  • Investigating chromatin remodelling by the Swi-Snf and Tup1-Cyc8 complexes 

    AL-HUSSAIN, MOHAMED MUBARAK (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Microbiology, 2020)
    Swi-Snf is an ATP-dependent chromatin remodelling complex which generally acts as a co-activator of gene transcription via its removal of promoter nucleosomes. Conversely, Tup1-Cyc8 (Ssn6) is a co-repressor complex which ...
  • De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences 

    Mc Lysaght, Aoife (2020)
    Recent evidence demonstrates that novel protein-coding genes can arise de novo from non- genic loci. This evolutionary innovation is thought to be facilitated by the pervasive translation of non-genic transcripts, which ...
  • Unravelling a food derived bioactive peptide with dual functionality of antimicrobial and immunomodulatory properties 

    MOHAN, NIAMH MAIRE (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Microbiology, 2020)
    In this thesis, a computational data mining and feature based approach to unravel the abundance of unexplored peptides from nature and to identify potent, novel antimicrobial peptides (AMPs) from phyto-proteins is proposed. ...

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