Network Physiology in Aging and Frailty: The Grand Challenge of Physiological Reserve in Older Adults
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2021Author:
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Romero-Ortuño, R., Martínez-Velilla, N., Sutton, R., Ungar, A., Fedorowski, A., Galvin, R., Theou, O., Davies, A., Reilly, R.B., Claassen, J., Kelly, Á.M., Ivanov, P.Ch., Network Physiology in Aging and Frailty: The Grand Challenge of Physiological Reserve in Older Adults, Frontiers in Network Physiology: Networks in Aging and Frailty, 2021Download Item:
144. FNP Grand Challenge reserve.PDF (Published (author's copy) - Peer Reviewed) 202.2Kb
Abstract:
In this Specialty Grand Challenge, we outline our vision of the current challenges in the field of Network Physiology as applied to aging and frailty. An expected development in this field for the 21st century is the modelling of the widely used (but still poorly understood) concept of ‘physiological reserve’ in relation to the wide heterogeneity in health status that exists between older adults of the same chronological age.
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https://www.frontiersin.org/articles/10.3389/fnetp.2021.712430/fullhttp://hdl.handle.net/2262/96615
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Grant Number
Health Research Board (HRB)
RL-2020-010 ILP-HSR-2017-021
Science Foundation Ireland (SFI)
18/FRL/6188 20/COV/8493 19/FFP/6867
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http://people.tcd.ie/romeroorDescription:
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Author: Romero-Ortuno, Roman
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Journal ArticleURI:
https://www.frontiersin.org/articles/10.3389/fnetp.2021.712430/fullhttp://hdl.handle.net/2262/96615
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Frontiers in Network Physiology: Networks in Aging and Frailty;Availability:
Full text availableKeywords:
Aging, Frailty, Network physiology, Reserve, Resilience, Dynamic couplingSubject (TCD):
AgeingDOI:
10.3389/fnetp.2021.712430Licences: