Browsing Medical Gerontology (Scholarly Publications) by Date of Publication
Now showing items 1-20 of 338
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Integrating genotypic data with transcriptomic and proteomic data.
(2002)Historically genotypic variation has been detected at the phenotypic level, at the metabolic level, and at the protein chemistry level. Advances in technology have allowed its direct visualisation at the level of DNA ... -
A prospective evaluation of bone mineral density measurement in females who have fallen
(2003)Background: the National Service Framework for Older Persons recognises the relationship between falls and osteoporosis; however, the best method for the evaluation of bone mineral density measurement in fallers is unclear. ... -
The use of an implantable loop recorder in the investigation of unexplained syncope in older people
(2003)Introduction: Reveal is a patient activated implantable loop recorder device with an 18 month battery life now available to assist in the diagnosis of suspected syncope or arrhythmias. We present our experience using this ... -
24-hour ambulatory electrocardiographic monitoring is unhelpful in the investigation of older persons with recurrent falls
(2005)Background: although frequently used in the assessment of patients with falls, it is unclear whether 24-hour ambulatory electrocardiography contributes to their assessment in older persons. Objective: to ... -
Patients with recurrent falls attending Accident & Emergency benefit from multifactorial intervention - a randomised controlled trial
(2005)OBJECTIVES: To determine the effectiveness of multifactorial intervention to prevent falls in cognitively intact older persons with recurrent falls. DESIGN: Randomised controlled trial of multifactorial (medical, physiotherapy ... -
Incidence and prediction of falls in dementia: a prospective study in older
(2009)Background: Falls are a major cause of morbidity and mortality in dementia, but there have been no prospective studies of risk factors for falling specific to this patient population, and no successful falls interventio ... -
A mathematical model of ageing-related and cortisol induced hippocampal dysfunction.
(BioMed Central, 2009)Background The hippocampus is essential for declarative memory synthesis and is a core pathological substrate for Alzheimer's disease (AD), the most common aging-related dementing disease. Acute increases in plasma cortisol ... -
Mayer Wave Activity in Vasodepressor Carotid Sinus Hypersensitivity
(2010)Aims Mayer waves are low frequency blood pressure waves, whose modulation involves central/peripheral baroreflex pathways. Although vasodepressor carotid sinus hypersensitivity (VDCSH) is a common hypotensive disorder in ... -
Alterations in the blood brain barrier in ageing cerebral cortex in relationship to Alzheimer-type pathology: a study in the MRC-CFAS population neuropathology cohort
(Elsevier, 2011)Impairment of the blood brain barrier (BBB) in human brain ageing and its relationship to Alzheimer-type pathology remains poorly defined. We have investigated the BBB in temporal cortex of brain donations from a ... -
Orthostatic haemodynamics may be impaired in frailty.
(2011)Background: orthostatic hypotension (OH) is a physical sign that reflects a final common pathway of various forms of disordered physiology, which is the hallmark of geriatric frailty. Fried et al. recognise three increasing ... -
Continuous noninvasive orthostatic blood pressure measurements and their relationship with orthostatic intolerance, falls, and frailty in older people.
(American Geriatrics Society, 2011)OBJECTIVES: To identify morphological orthostatic blood pressure (BP) phenotypes in older people and assess their correlation with orthostatic intolerance (OI), falls, and frailty and to compare the discriminatory performance ... -
Retirement and Labour Market Participation
(TILDA, 2011)Labour market participation of older people is important from the perspective of the individual and the macroeconomy. At an individual level, participation in the labour market can be associated with increased resources ... -
Growing Up in Ireland - National Longitudinal Study of Children: Overweight and Obesity Among 9-Year-Olds
(Stationery Office, 2011) -
Hand-held dynamometry: tester strength is paramount, even in frail populations.
(2011)To determine test-retest and inter-rater reliability of hand-held dynamometry when used to measure knee--extensor strength in patients with advanced cancer. SUBJECTS: Adults with metastatic or locally advanced cancer ... -
The Impact of Parental Earnings and Education on the Schooling of Children
(University College Dublin, 2011)This paper addresses the intergenerational transmission of education and investigates the extent to which early school leaving (at age 16) may be due to variations in parental background. An important contribution of ... -
Fifty plus in Ireland 2011: First results from The Irish Longitudinal Study on Ageing (TILDA)
(Trinity College Dublin, 2011)The Irish Longitudinal Study on Ageing (TILDA) is a large-scale, nationally representative study of people aged 50 and over in Ireland. It is the most ambitious study of ageing ever carried out in Ireland and represents ...
