The frailty index in Europeans: association with age and mortality.
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Romero-Ortuno, R. & Kenny, R.A. The frailty index in Europeans: association with age and mortality., Age and Ageing, 41, 2012, 684-689Download Item:
Abstract:
Background: the frailty index (FI) is an approach to the operationalisation of frailty based on accumulation of deficits.
It has been less studied in Europeans.
Objective: to construct sex-specific FIs from a large sample of Europeans and study their associations with age and
mortality.
Design: longitudinal population-based survey.
Setting: the Survey of Health, Ageing and Retirement in Europe (SHARE, http://share-dev.mpisoc.mpg.de/).
Subjects: a total of 16,217 females and 13,688 males aged ≥50 from wave 1 (2004 –05). Mortality data were collected
between 2005 and 2006 (mean follow-up: 2.4 years).
Methods: regression curve estimations between age and an FI constructed as per the standard procedure. Logistic regressions
were used to assess the relative effects of age and the FI towards mortality.
Results: in both sexes, there was a significant non-linear association between age and the FI (females: quadratic R2 = 0.20,
P < 0.001; males: quadratic R2 = 0.14, P < 0.001). Overall, the FI was a much stronger predictor of mortality than age, even
after adjusting for the latter (females: age-adjusted OR 100.5, 95% confidence interval (CI): 46.3–218.2, P < 0.001; males:
age-adjusted OR 221.1, 95% CI: 106.7–458.4, P < 0.001).
Conclusion: the FI had the expected properties in this large sample of Europeans.
Author's Homepage:
http://people.tcd.ie/rkennyhttp://people.tcd.ie/romeroor
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Author: ROMERO-ORTUNO, ROMAN; KENNY, ROSE ANNE
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Age and Ageing;41;
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Full text availableKeywords:
Frail elderly, Health status index, Mortality, Frailty index, Sex differences, ElderlyMetadata
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