Development of the recombinant Semliki Forest virus vector as a gene therapy agent for the central nervous system
Citation:
Alan Jerusalmi, 'Development of the recombinant Semliki Forest virus vector as a gene therapy agent for the central nervous system', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2004, pp 263Download Item:
Jerusalmi TCD THESIS 7511 Development of.pdf (PDF) 219.8Mb
Abstract:
Multiple sclerosis (MS) is a neurological disease of the central nervous system (CNS),
and a major cause of disability in young adults. It is characterized by the presence of inflammatory infiltrates containing autoreactive T cells, resulting in demyelination and axonal loss within the CNS. One of the greatest challenges in the treatment of MS is to get the therapeutic agent to successfully cross the bloodrbrain barrier, and exert an activity inside the CNS.
Author: Jerusalmi, Alan
Advisor:
Atkins, GregQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical MicrobiologyNote:
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Full text availableKeywords:
Microbiology, Ph.D., Ph.D. Trinity College DublinLicences: