DEVELOPMENT OF MAGNETORESISTIVE SENSORS FOR NANOWIRE DETECTION TARGETED AT BIOLOGICAL APPLICATIONS
Citation:
Nigel Carroll, 'DEVELOPMENT OF MAGNETORESISTIVE SENSORS FOR NANOWIRE DETECTION TARGETED AT BIOLOGICAL APPLICATIONS'Download Item:
Abstract:
This research project has been focused on developing technologies for the detection
of single segment and multi-segment magnetic nanowires using yoke shaped GMR
sensors and TMR MgO-barrier magnetic tunnel junction sensors integrated into a
microfluidic channel. The leading questions has been firstly can one detect the stray
field of the single-segment magnetic nanowire as it passes over the sensor and secondly
can one detect the magnetic segments within a multi-segment nanowire and distinguish
different signal response signatures between a single segment nanowire and multisegmented
nanowire. Over the past 20 years there has been a focus in utilizing
advances in magnetoresistive sensors, nanowires and microfluidics leading to simpler
and less expensive instrumentation. These technologies have been integrated into labon-
chip biomedical platforms for applications such as magnetocardiography (MCG),
magnetic cytometry (Pannetier-Lecoeur et al 2011 and Freitas et al 2012) [1, 2]. To
capture and analyse the signals, a dedicated detection system is implemented. The
detection system comprises of an interface for sensors and a microfluidic chip, lownoise
pre and post-amplifiers, a data acquisition card, a microscope and camera. Signal
detection experiments are carried out with two GMR sensors configured as a lateral
gradiometer, which enabled us to detect single segment nanowires as they pass over
the sensor. Detection of single metal nanowires has been demonstrated at arbitrary
stand-off distance within the microfluidic channel. Two magnetic-segment “bar” code
events have also been detected using the gradiometer with focused flow.
Sponsor
Grant Number
European Commission
EU FP7 NMP4-LA-2010-246479
Author: Carroll, Nigel
Advisor:
Stamenov, PlamenCoey, Michael
Qualification name:
Doctor of Philosophy (Ph.D.)Type of material:
ThesisAvailability:
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