Mechanical & Manufacturing Eng
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Mechanical & Manufacturing Eng (Scholarly Publications)
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Mechanical & Manufacturing Eng (Theses and Dissertations)
Mechanical & Manufacturing Eng (Theses and Dissertations)
Recent Submissions
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Investigation into the collagen fibre-mediated fatigue mechanics of bovine pericardium for use in bioprosthetic heart valves
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)Bioprosthetic heart valve replacements have long been associated with inadequate durability in vivo, owing primarily to mechanical damage and calcification of the glutaraldehyde-fixed bovine pericardial leaflets (GLBP). ... -
Fabrication and biocompatibility of electroconductive silk fibroin/pedot: Pss composites for corneal epithelial regeneration
(2020)The aim of this study was to develop matrices that can support human corneal epithelial cells and innervation by incorporating a conducting polymer, poly(3,4-ethylenedioxythiophene) poly(styrene sulfonate) (PEDOT:PSS), ... -
Retinoic Acid Enhances the Differentiation of Adipose-Derived Stem Cells to Keratocytes In Vitro
(2017)Purpose: All-trans retinoic acid (RA) supplementation was investigated as a method of enhancing the differentiation of human adipose-derived stem cells (ASCs) to corneal keratocytes in vitro, in combination with a chemically ... -
Dextran Preserves Native Corneal Structure During Decellularization.
(2016)Corneal decellularization has become an increasingly popular technique for generating scaffolds for corneal regeneration. Most decellularization procedures result in tissue swelling, thus limiting their application. Here, ... -
Silk fibroin safety in the eye: A review that highlights a concern
(2020)The biomedical use of silk as a suture dates back to antiquity. Fibroin is the structural element that determines the strength of silk and here we consider the safety of fibroin in its role in ophthalmology. The high ...