Recent Submissions

  • Biophysical Regulation of Stem Cell Osteogenic Lineage Commitment: A Role for the Cytoskeleton 

    STAVENSCHI, ELENA (Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2019)
    Osteoporosis is a debilitating disease characterised by weakened bone architecture due to increased resorption activity of osteoclasts and diminished bone deposition by mesenchymal stem cell (MSC) derived osteoblasts. ...
  • Fundamental Insights into Arterial Remodelling; Strain-Mediated Degradation of Arterial Collagen 

    GAUL, ROBERT (Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2019)
    Maladaptive remodelling of structurally significant collagen fibres in the arterial wall is believed to play a critical role in the development and progression of degenerative arterial disease. A greater understanding of ...
  • Biomechanics of Repair in Invertebrates 

    O'NEILL, MAEVE (Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2019)
    Repair is a ubiquitous process in nature, and it is one of the many features of biological materials that humans are constantly attempting to recreate. Though the process of repair has been studied in mammals, very little ...
  • Prediciton of fatigue failure in engineering components using the finite element method 

    Wang, Ge (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2000)
    Prediction of fatigue failure in engineering artefects is becoming increasingly important as we enter the third millennium; more catastrophic fatigue failures will occur as engineers push the limits of design even further ...
  • Investigating the applicability of single-channel electroencephalography in cochlear implant patients 

    Valdes, Alejandro Lopez (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2017)
    Hearing impairment affects over 5% of the population worldwide. Namely, about a quarter of a million adults in Ireland are estimated to have permanent hearing impairment due mainly to ageing and/or noise exposure. Cochlear ...

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