RSS 1.0Mechanical & Manufacturing Eng (Scholarly Publications)
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On the assessment of a VOF based compressive interface capturing scheme for the analysis of bubble impact on and bounce from a flat horizontal surface
(2014)The process of free rise, collision on and bounce from a solid horizontal surface for a single isolated bubble is investigated by numerical simulations based on the Volume of Fluid method (VOF). The volume fraction ... -
Heat transfer and flow structure evaluation of a synthetic jet emanating from a planar heat sink
(2014)Direct impinging synthetic jets are a proven method for heat transfer enhancement, and have been subject to extensive research. However, despite the vast amount of research into direct synthetic jet impingement, there ... -
Thermal management using pulsating jet cooling technology
(2014)The existing methods of heat removal from compact electronic devises are known to be deficient as the evolving technology demands more power density and accordingly better cooling techniques. Impinging jets can be used as ... -
Altering the architecture of tissue engineered hypertrophic cartilaginous grafts facilitates vascularisation and accelerates mineralisation.
(2014)Cartilaginous tissues engineered using mesenchymal stem cells (MSCs) can be leveraged to generate bone in vivo by executing an endochondral program, leading to increased interest in the use of such hypertrophic grafts ... -
Identification of mechanosensitive genes during skeletal development: Alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways
(2014)Background Mechanical stimulation is necessary for regulating correct formation of the skeleton. Here we test the hypothesis that mechanical stimulation of the embryonic skeletal system impacts expression levels of genes ... -
Feasibility Study and Cost-Benefit Analysis of Tidal Energy: A Case Study for Ireland
(2012)Ireland set out to produce 33% of its electricity demand from renewable sources by 2020 and reduce emissions to the level of 1990 in accordance with the Kyoto agreement. These targets require investments in a diverse ... -
General Reduced-Order Model to Design and Operate Synthetic Jet Actuators
(2012)Synthetic jets are used in various applicat ions from flow contro l to thermal management of electronics. Controlling the jet operating point using a simple voltage to velocity calibration becomes unreliable in case ... -
Experimental Validation of a Computational Fluid Dynamics Methodology for Transitional Flow Heat Transfer Characteristics of a Steady Impinging Jet
(2014)This paper presents a computational fluid dynamics (CFD) methodology to accurately predict the heat transfer characteristics of an unconfined steady impinging air jet in the transitional flow regime, impinging on a planar ... -
Flow regime characterisation of an impinging axisymmetric synthetic jet
(2013)Impinging synthetic jets have excellent potential for energy-efficient local cooling in confined geometries. For a given geometry, synthetic jet flows are mainly characterised by the Reynolds number and the ratio of stroke ... -
Scaling of Convective Heat Transfer Enhancement Due to Flow Pulsation in an Axisymmetric Impinging Jet
(2013)Impinging jets are widely used to achieve a high local convective heat flux, with applications in high power density electronics and various other industrial fields. The heat transfer to steady impinging jets has been ... -
A validated numerical-experimental design methodology for a movable supersonic ejector compressor for waste-heat recovery
(2013)The aim of this paper is to develop the technical knowledge, especially the optimum geometries, for the design and manufacturing of a supersonic gas-gas ejecto r for a waste heat driven vehicle cooling system. Although ... -
A comparison of self-assembly and hydrogel encapsulation as a means to engineer functional cartilaginous grafts using culture expanded chondrocytes.
(2014)Despite an increased interest in the use of hydrogel encapsulation and cellular self-assembly (often termed "self-aggregating" or "scaffold-free" approaches) for tissue-engineering applications, to the best of our knowledge, ... -
Exploring the roles of integrin binding and cytoskeletal reorganization during mesenchymal stem cell mechanotransduction in soft and stiff hydrogels subjected to dynamic compression.
(2014)The objective of this study was to explore how the response of mesenchymal stem cells (MSCs) to dynamic compression (DC) depends on their pericellular environment and the development of their cytoskeleton. MSCs were first ... -
Infrapatellar Fat Pad-Derived Stem Cells Maintain Their Chondrogenic Capacity in Disease and Can be Used to Engineer Cartilaginous Grafts of Clinically Relevant Dimensions.
(2014)A therapy for regenerating large cartilaginous lesions within the articular surface of osteoarthritic joints remains elusive. While tissue engineering strategies such as matrix-assisted autologous chondrocyte implantation ... -
Substrate stiffness and oxygen availability as regulators of mesenchymal stem cell differentiation within a mechanically loaded bone chamber.
(2014)M echanical stimuli such as tissue deformation and fluid flow are often implicated as regulators of mesenchymal stem cell (MSC) differentiation during regenerative events in vivo . However , in vitro studies ... -
Controlled release of transforming growth factor-ß3 from cartilage-extra-cellular-matrix-derived scaffolds to promote chondrogenesis of human-joint-tissue-derived stem cells.
(2014)Abstract: The objective of this study was to develop a scaffold derived from cartilaginous extracellular matrix (ECM) that could be used as a growth factor delivery system to promote chondrogenesis of stem cells. ... -
Engineering cartilage or endochondral bone: A comparison of different naturally derived hydrogels.
(2015)Cartilaginous tissues engineered using mesenchymal stem cells (MSCs) have been shown to generate bone in vivo by executing an endochondral programme. This may hinder the use of MSCs for articular cartilage regeneration, ... -
Optimum Parameters for Freeze-Drying Decellularized Arterial Scaffolds
(2013)Decellularized arterial scaffolds have achieved success in advancing toward clinical use as vascular grafts. However, concerns remain regarding long-term preservation and sterilization of these scaffolds. Freeze drying ... -
An Experimental Study to Determine the Optimal Access Route for Renal Artery Interventions
(2013)Objective The standard approach for endovascular treatment of the renal artery is access via the common femoral artery. However, approximately one in eight patients have a renal artery take-off angle that is less than ... -
Observations of Surface Acoustic Wave Strain and Resistive Strain Measurements on Broaching Tools for Process Monitoring
(2014)The monitoring of high end material removal processes continues to develop to greater levels of technical sophistication which in turn enable greater levels of insight into the process phenomena occurring at the tool-chip ...