Staying alive: defensive strategies in the BCL-2 family playbook.
Item Type:Journal Article
Citation:Cullen SP, Henry CM, Martin SJ, Staying alive: defensive strategies in the BCL-2 family playbook., Molecular cell, 44, 4, 2011, 509-10
1-s2.0-S1097276511008471-main.pdf (PDF) 217.5Kb
Much debate surrounds how prosurvival members of the BCL-2 family repress opening of the BAX/BAK channel to block apoptosis; in this issue Llambi et al. (2011) identify two modes of apoptosis inhibition that exhibit surprisingly different behavior upon repeat proapoptotic challenges by BH3-only proteins.
Science Foundation Ireland (SFI)
Author: MARTIN, SEAMUS
Type of material:Journal Article
Series/Report no:Molecular cell
Availability:Full text available