Now showing items 1-3 of 3

    • Characterising Macrophage Immunometabolism in Mycobacterium tuberculosis and HIV Co-Infection 

      Brown, Kevin (Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2024)
      Introduction Tuberculosis (TB) and HIV are leading infection-related causes of global mortality and result in an enormous amount of suffering and economic loss. Available TB treatment strategies are inadequate, and vaccination ...
    • Early Immune Responses to Emerging and Enduring Respiratory Pathogens 

      Grant, Conor Francis (Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2024)
      For most of recent history, Tuberculosis (TB) has been the leading cause of death by an infective agent worldwide. Tuberculosis is caused by Mycobacterium tuberculosis (Mtb), which infects human lungs following respiratory ...
    • An investigation of epigenetic effects in Atherosclerosis 

      Byrne, Mikaela (Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2017)
      Epigenetic mechanisms may explain some of the missing heritability associated with CVD and how external factors such as diet, environment and lifestyle contribute to disease development and progression. This thesis aimed ...