Browsing Clinical Medicine by Author "Marignol, Laure"
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A promising hypoxia-inducible suicide gene therapy strategy for prostate cancer
Marignol, Laure (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2008)Gene therapy targeted to hypoxic tumour cells may allow selective killing of malignant cells. The induction of gene expression under hypoxic conditions is governed by the activation of hypoxia-inducible factor 1 and its ...