Browsing RSS Feeds by Subject "Obesity"
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Antibiotic use in early childhood and risk of obesity: Longitudinal analysis of a national cohort
(2019)Background: Taking oral antibiotics during childhood has been linked with an increased risk of childhood obesity. This study assessed any potential association in number of courses of antibiotics taken between 2-3 and 4-5 ... -
Barriers and facilitators to implementation of menu labelling interventions to support healthy food choices: a mixed methods systematic review protocol
(2018)Background: Menu labelling is continuing to gather public and legislative support as one of the potential environmental strategies for addressing the obesity pandemic. However, issues relating to implementation have been ... -
Dietary fat, abdominal obesity and smoking modulate the relationship between plasma complement component 3 concentrations and metabolic syndrome risk
(2012)Objective: Chronic inflammation plays a role in the pathogenesis of metabolic syndrome (MetS) and cardiovascular disease (CVD). Complement component 3 (C3) is a novel cardiometabolic risk factor. Whether dietary fat intake ... -
Diverse Immunoregulatory Roles of Oxysterols - The Oxidized Cholesterol Metabolites
(2020)Intermediates of both cholesterol synthesis and cholesterol metabolism can have diverse roles in the control of cellular processes that go beyond the control of cholesterol homeostasis. For example, oxidized forms of ... -
Do ADHD-impulsivity and BMI have shared polygenic and neural correlates?
(2019)There is an extensive body of literature linking ADHD to overweight and obesity. Research indicates that impulsivity features of ADHD account for a degree of this overlap. The neural and polygenic correlates of this ... -
Editorial: T cell alterations in adipose tissue during obesity, HIV, and cancer
(Frontiers Media, 2019-05-28)This collection of articles is designed to foster understanding of the variety and function of T cells in adipose from different species in different disease states. This work originally developed from the obesity epidemic. ... -
?Examining the connectivity between different cellular processes in the Barrett tissue microenvironment: energy metabolism, hypoxia, inflammation, p53 and obesity?.
(2016)In Barrett associated tumorigenesis, oxidative phosphorylation and glycolysis are reprogrammed early in the disease sequence and act mutually to promote disease progression. However, the link between energy metabolism and ... -
Fatty acid synthase downregulation contributes to acute lung injury in murine diet-induced obesity
(2019)The prevalence of obesity is rising worldwide, and obese patients constitute a specific population in the intensive care unit. Acute respiratory distress syndrome (ARDS) incidence is increased in obese patients. Exposure ... -
A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder.
(2015)Background Obesity is strongly associated with major depressive disorder (MDD) and various other diseases. Genome-wide association studies have identified multiple risk loci robustly associated with body mass index (BMI). ... -
Interleukin-36 cytokines alter the intestinal microbiome and can protect against obesity and metabolic dysfunction.
(2019)Members of the interleukin-1 (IL-1) family are important mediators of obesity and metabolic disease and have been described to often play opposing roles. Here we report that the interleukin-36 (IL-36) subfamily can play a ... -
Maternal educational inequalities in measured body mass index trajectories in three European countries
(2019)Background: Social inequalities in the prevalence of childhood overweight and obesity are well‐established, but less is known about when the social gradient first emerges and how it evolves across childhood and ... -
Overweight and obesity among older adults upon admission to hospital
(2011)Poor nutritional status, which includes both under- and over-nutrition, is associated with poor health outcomes. This cross-sectional study assessed the nutritional status of older patients admitted to an acute geriatric ... -
Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes
(2018)Objective: The inappropriate release of free fatty acids from obese adipose tissue stores has detrimental effects on metabolism, but key molecular mechanisms controlling FFA release from adipocytes remain undefined. ... -
Physical activity levels and body composition in children living in disadvantaged areas of urban India
(2010)Background: Recent studies on children attending private or governmental schools in India have reported increasing rates of obesity. The aim of this study was to examine body composition and activity levels of children ... -
Pro-inflammatory and tumour proliferative properties of excess visceral adipose tissue
(2011)Obesity has been associated with increased incidence and mortality of oesophageal and colorectal adenocarcinoma. Excess central adiposity may drive this association through an altered inflammatory milieu. Utilizing a unique ... -
Relationship between obesity and the risk of clinically significant depression: Mendelian randomisation study.
(2014)BACKGROUND: Obesity has been shown to be associated with depression and it has been suggested that higher body mass index (BMI) increases the risk of depression and other common mental disorders. However, the causal ... -
Role for Retinoic Acid-Related Orphan Receptor Alpha (RORα) Expressing Macrophages in Diet-Induced Obesity
(2020)The transcription factor RORα plays an important role in regulating circadian rhythm, inflammation, metabolism, and cellular development. Herein we show a role for RORα-expressing macrophages in the adipose tissue in ... -
Socioeconomic status, non-communicable disease risk factors, and walking speed in older adults: multi-cohort population based study.
(British Medical Association, 2018)Objective: To assess the association of low socioeconomic status and risk factors for non-communicable diseases (diabetes, high alcohol intake, high blood pressure, obesity, physical inactivity, smoking) with loss of ... -
Tissue distribution of γδ T cell subsets in oesophageal adenocarcinoma
(2021)The global obesity epidemic is contributing to increased prevalence of diseases fuelled by chronic inflammation, including cancer. Oesophageal adenocarcinoma (OAC) is an obesity-associated malignancy with increasing ...