Browsing Microbiology by Author "Dorman, Charles"
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Consequences of producing DNA gyrase from a synthetic gyrBA operon in Salmonella enterica serovar Typhimurium
Dorman, Charles (2021)DNA gyrase is an essential type II topoisomerase that is composed of two subunits, GyrA and GyrB and has an A 2 B 2 structure. Although both subunits are required in equal proportions to form DNA gyrase, the gyrA and gyrB ... -
DNA supercoiling and transcription: a two-way street
Dorman, Charles (2019)Background : The processes of DNA supercoiling and transcription are interdependent because the movement of a transcription elongation complex simultaneously induces under- and over winding of the DNA duplex and because ... -
DNA topology and adaptation of Salmonella typhimurium to an intracellular environment
Dorman, Charles (2000) -
Monaco Declaration - Advancing Human Health and well-being by Preventing Ocean Pollution
Dorman, Charles (2021) -
Network rewiring: physiological consequences of reciprocally exchanging the physical locations and growth-phase-dependent expression patterns of the Salmonella fis and dps genes
Dorman, Charles (2020)The Fis nucleoid-associated protein controls the expression of a large and diverse regulon of genes in Gram-negative bacteria. Fis production is normally maximal in bacteria during the early exponential phase of batch ... -
Regulatory hierarchies controlling virulence gene expression in Shigella flexneri and Vibrio cholerae
Dorman, Charles; Dorman, Matthew (2018)Gram-negative enteropathogenic bacteria use a variety of strategies to cause disease in the human host and gene regulation in some form is typically a part of the strategy. This article will compare the toxin-based infection ... -
When is a transcription factor a NAP?
Dorman, Charles (2020)Proteins that regulate transcription often also play an architectural role in the genome. Thus, it has been difficult to define with precision the distinctions between transcription factors and nucleoid-associated proteins ...