Browsing Microbiology by Title
Now showing items 21-40 of 320
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Antimicrobial peptide preventing beer spoilage
(Trinity College (Dublin, Ireland). Department of Microbiology, 2012)Beer spoilage micro-organisms (BSMs) are a common threat to Master Brewers worldwide. Numerous studies have been carried out to date to overcome this problem, yet the most common preventative measure is the addition of ... -
Antimitotic herbicides bind to an unidentifed site on malarial parasite tubulin and block development of liver-stage Plasmodium parasites.
(2013)Malarial parasites are exquisitely susceptible to a number of microtubule inhibitors but most of these compounds also affect human microtubules. Herbicides of the dinitroaniline and phosphorothioamidate classes however ... -
BABAR: an R package to simplify the normalisation of common reference design microarray-based transcriptomic datasets.
(BioMed Central, 2010)BACKGROUND: The development of DNA microarrays has facilitated the generation of hundreds of thousands of transcriptomic datasets. The use of a common reference microarray design allows existing transcriptomic data to be ... -
Bacterial DNA topology and infectious disease
(2009)he gram-negative bacterium Escherichia coli and its close relative Salmonella enterica have made important contributions historically to our understanding of how bacteria control DNA supercoiling and of how supercoiling ... -
Bacterial regulon evolution: distinct responses and roles for the identical OmpR proteins of Salmonella Typhimurium and Escherichia coli in the acid stress response
(2014)The evolution of new gene networks is a primary source of genetic innovation that allows bacteria to explore and exploit new niches, including pathogenic interactions with host organisms. For example, the archetypal DNA ... -
Beta-neurexin is a ligand for the Staphylococcus aureus MSCRAMM SdrC
(2010)Gram-positive bacteria contain a family of surface proteins that are covalently anchored to the cell wall of the organism. These cell-wall anchored (CWA) proteins appear to play key roles in the interactions between ... -
Biasing switching outcomes in the Escherichia coli fim site-specific recombination system through DNA supercoiling and nucleoid-associated proteins
(Trinity College (Dublin, Ireland). Department of Microbiology, 2010)Type 1 fimbriae are typically expressed in nutrient poor environments and facilitate colonization through attachment when the bacterium can no longer support a motile lifestyle that demands a high metabolic flux. They play ... -
The binding of calcium to the B-repeat segment of SdrD, a cell surface protein of Staphylococcus aureus
(1998)In the Sdr family of Staphylococcus aureus cell surface proteins, three recently cloned members (Josefsson, E., McCrea, K., Ni Eidhin, D., O'Connell, D., Cox, J. A., Hook, M., and Foster, T. (1998) Microbiology, in press) ... -
Biogenesis of histone mRNAs in the yeast Saccharomyces cerevisiae
(Trinity College (Dublin, Ireland). Department of Microbiology, 2007)The typical eukaryotic human diploid cell contains 3.2x10 9 base pairs of deoxyribonucleic acid (DNA) which, if presented in an extended form, would measure 1.2m in length. The large amount of DNA is tightly wrapped and ... -
Biomass to biofuel : the engineering of Saccharomyces species for the co-fermentation of cellulose and xylose
(Trinity College (Dublin, Ireland). Department of Microbiology, 2015)Lignocellulose represents one of the most abundant biomass sources in the world. Its renewable and abundant nature makes it a prime target for use in bioethanol production. The efficient conversion of lignocellulosic biomass ... -
Biomass to biofuel : towards the bioengineering of Saccharomyces species for cellulose degradation
(Trinity College (Dublin, Ireland). Department of Microbiology, 2011)Cellulose is the most abundant polysaccharide on earth and therefore represents a major reservoir of sugar that could be potentially converted to alcohol and used as a fuel source. The filamentous fungus Trichoderma reesei ... -
Broad scale redistribution of mRNA abundance and transcriptional machinery in response to growth rate in Salmonella enterica serovar Typhimurium
(2017)We have investigated the connection between the four-dimensional architecture of the bacterial nucleoid and the organism's global gene expression programme. By localizing the transcription machinery and the transcriptional ... -
Characterisation of genotypic and phenotypic differences between Candida dubliniensis and Candida albicans
(Trinity College (Dublin, Ireland). Department of Microbiology, 2001)Summary -Candida dubliniensis is a recently described Candida species associated with oral candidosis in Human Immunodeficiency Virus (HIV)-infected and AIDS patients. The phylogenetic position of C. dubliniensis has ... -
Characterisation of SdrC, SdrD and SdrE from the serine-aspartate repeat family of Staphylococcus auerus
(Trinity College (Dublin, Ireland). Department of Microbiology, 2001)Staphylococcus aureus is an important human pathogen. The ability of S. aureus to initiate infection is attributed at least partly to the expression of cell wall-associated proteins known as MSCRAMMs (microbial surface ... -
Characterisation of Sfh, a novel H-NS-like protein
(Trinity College (Dublin, Ireland). Department of Microbiology, 2006)Members of the H-NS protein family are widespread among Gram-negative bacteria and are known to influence gene expression at a global level. Shigella flexneri serotype 2a strain 2457T expresses three members of the H-NS ... -
Characterisation of the Rns transcriptional regulator of enterotoxigenic Escherichia coli and regulationf of CS1 fimbrial expression
(Trinity College (Dublin, Ireland). Department of Microbiology, 2008)Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhoea amongst children in developing countries and travellers to such countries. Virulence in ETEC is dependent on both toxin production and adherence of the ...